Literature DB >> 2534062

An ethidium bromide induced mutant of Neurospora crassa defective in mitochondrial DNA.

F D Niagro1, N C Mishra.   

Abstract

Slow growing mutants of Neurospora crassa were obtained by ethidium bromide treatment of the wild type strain. A particular mutant ER-3 showed stopper phenotype accompanied by deficient cytochrome spectra. The mutant showed an altered restriction pattern of the mtDNA which indicated a deletion of 25,000 bp. The phenotype of the ethidium bromide induced mutant ER-3 seem to be related to the loss of several essential genes due to a deletion in its mtDNA.

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Year:  1989        PMID： 2534062     DOI： 10.1007/bf00422117

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  13 in total

1.  Mendelian and Non-Mendelian Factors Affecting the Cytochrome System in Neurospora Crassa.

Authors:  M B Mitchell; H K Mitchell; A Tissieres
Journal:  Proc Natl Acad Sci U S A       Date:  1953-07       Impact factor: 11.205

Review 2.  Genetics of mitochondrial biogenesis.

Authors:  A Tzagoloff; A M Myers
Journal:  Annu Rev Biochem       Date:  1986       Impact factor: 23.643

3.  Molecular characterization of the mitochondrial DNA of a new stopper mutant ER-3 of Neurospora crassa.

Authors:  A Almasan; N C Mishra
Journal:  Genetics       Date:  1988-12       Impact factor: 4.562

Review 4.  Gene transfer in fungi.

Authors:  N C Mishra
Journal:  Adv Genet       Date:  1985       Impact factor: 1.944

5.  Structure and expression of the overlapping ND4L and ND5 genes of Neurospora crassa mitochondria.

Authors:  M A Nelson; G Macino
Journal:  Mol Gen Genet       Date:  1987-02

6.  Intramolecular recombination as a source of mitochondrial chromosome heteromorphism in Neurospora.

Authors:  S R Gross; T S Hsieh; P H Levine
Journal:  Cell       Date:  1984-08       Impact factor: 41.582

7.  Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies.

Authors:  I J Holt; A E Harding; J A Morgan-Hughes
Journal:  Nature       Date:  1988-02-25       Impact factor: 49.962

8.  Cytochrome oxidase subunit 2 gene in Neurospora crassa mitochondria.

Authors:  G Macino; G Morelli
Journal:  J Biol Chem       Date:  1983-11-10       Impact factor: 5.157

9.  The E35 stopper mutant of Neurospora crassa: precise localization of deletion endpoints in mitochondrial DNA and evidence that the deleted DNA codes for a subunit of NADH dehydrogenase.

Authors:  H de Vries; B Alzner-DeWeerd; C A Breitenberger; D D Chang; J C de Jonge; U L RajBhandary
Journal:  EMBO J       Date:  1986-04       Impact factor: 11.598

10.  Studies on a cytoplasmic character in Neurospora crassa.

Authors:  L Garnjobst; J F Wilson; E L Tatum
Journal:  J Cell Biol       Date:  1965-08       Impact factor: 10.539
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  2 in total

1.  Deletion of a novel F-box protein, MUS-10, in Neurospora crassa leads to altered mitochondrial morphology, instability of mtDNA and senescence.

Authors:  Akihiro Kato; Kiminori Kurashima; Michael Chae; Satoshi Sawada; Shin Hatakeyama; Shuuitsu Tanaka; Hirokazu Inoue
Journal:  Genetics       Date:  2010-06-01       Impact factor: 4.562

2.  Recombination by sequence repeats with formation of suppressive or residual mitochondrial DNA in Neurospora.

Authors:  A Almasan; N C Mishra
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205
  2 in total

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