| Literature DB >> 25337299 |
Xiang Li1, Wei-Hua Liao2, Jian-Hua Zhou1, Bao-An Liu1, Ji-Fang Wen1, Zhong-Liang Hu1.
Abstract
Extranodal natural killer (NK)/T-cell lymphoma is a very aggressive malignant neoplasia with a poor prognosis. Herein we reported a case of NK/T cell lymphoma involving mediastinum. It was a 28-year-old Chinese male patient. The tumor cells were medium-sized, had irregularly folded nuclei, and inconspicuous or small nucleoli with coagulative necrosis. The tumor cells were positive for CD3ε, TIA-1, but negative for CD56. In situ hybridization revealed that tumor cells also expressed Epstein-Barr virus encoded RNA. To our knowledge, this is the first case of NK/T cell lymphoma involving mediastinum.Entities:
Keywords: Epstein-Barr virus; NK/T cell lymphoma; mediastinum
Mesh:
Substances:
Year: 2014 PMID: 25337299 PMCID: PMC4203270
Source DB: PubMed Journal: Int J Clin Exp Pathol ISSN: 1936-2625