Literature DB >> 25337299

NK/T cell lymphoma involving mediastinum: report of a case and review of literature.

Xiang Li1, Wei-Hua Liao2, Jian-Hua Zhou1, Bao-An Liu1, Ji-Fang Wen1, Zhong-Liang Hu1.   

Abstract

Extranodal natural killer (NK)/T-cell lymphoma is a very aggressive malignant neoplasia with a poor prognosis. Herein we reported a case of NK/T cell lymphoma involving mediastinum. It was a 28-year-old Chinese male patient. The tumor cells were medium-sized, had irregularly folded nuclei, and inconspicuous or small nucleoli with coagulative necrosis. The tumor cells were positive for CD3ε, TIA-1, but negative for CD56. In situ hybridization revealed that tumor cells also expressed Epstein-Barr virus encoded RNA. To our knowledge, this is the first case of NK/T cell lymphoma involving mediastinum.

Entities:  

Keywords:  Epstein-Barr virus; NK/T cell lymphoma; mediastinum

Mesh:

Substances:

Year:  2014        PMID: 25337299      PMCID: PMC4203270     

Source DB:  PubMed          Journal:  Int J Clin Exp Pathol        ISSN: 1936-2625


  5 in total

1.  Extranodal nasal-type natural killer/T-cell lymphoma masquerading as recalcitrant sinusitis.

Authors:  Young S Paik; Benjamin D Liess; Troy D Scheidt; Ellis A Ingram; Robert P Zitsch
Journal:  Head Neck       Date:  2010-02       Impact factor: 3.147

2.  Lymphoblastic lymphoma expressing natural killer cell phenotype with involvement of the mediastinum and nasal cavity.

Authors:  H Koita; J Suzumiya; K Ohshima; M Takeshita; N Kimura; M Kikuchi; M Koono
Journal:  Am J Surg Pathol       Date:  1997-02       Impact factor: 6.394

Review 3.  Nasal-type NK/T-cell lymphoma with palatal ulcer as the earliest clinical manifestation: a case report with literature review.

Authors:  Wenxia Meng; Yu Zhou; Hengyu Zhang; Lu Jiang; Zhi Wang; Xiaoying Li; Hongmei Zhou; Qianming Chen; Xin Zeng
Journal:  Pathol Oncol Res       Date:  2009-07-11       Impact factor: 3.201

Review 4.  Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm.

Authors:  J K Chan; V C Sin; K F Wong; C S Ng; W Y Tsang; C H Chan; M M Cheung; W H Lau
Journal:  Blood       Date:  1997-06-15       Impact factor: 22.113

5.  Blastic natural killer cell lymphoma arising from the mediastinum with terminal deoxynucleotidyl transferase expression.

Authors:  K Isobe; J I Tamaru; S Nakamura; J Itami; T Aruga; T Uno; S Yasuda; A Mikata; H Ito
Journal:  Pathol Int       Date:  2001-01       Impact factor: 2.534

  5 in total
  3 in total

1.  Two Cases of NK/T Cell Lymphoma Presenting as Chronic Rhinosinusitis.

Authors:  Rajat Thawani; Shishir Seth; Kuldeep Singh; Jayanta Patowary; Mano Bhadauria; Pratap Kishore Das
Journal:  Indian J Hematol Blood Transfus       Date:  2016-07-15       Impact factor: 0.900

Review 2.  Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases.

Authors:  Bradley M Haverkos; Zenggang Pan; Alejandro A Gru; Aharon G Freud; Rachel Rabinovitch; Meng Xu-Welliver; Brad Otto; Carlos Barrionuevo; Robert A Baiocchi; Rosemary Rochford; Pierluigi Porcu
Journal:  Curr Hematol Malig Rep       Date:  2016-12       Impact factor: 3.952

3.  Clinical characteristics and treatment of 69 patients with extranodal natural killer T-cell lymphoma.

Authors:  Yuyan Guo; Enxiao Li; Liping Song; Yinying Wu
Journal:  Mol Clin Oncol       Date:  2016-10-27
  3 in total

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