Literature DB >> 2533685

Antithrombin III substitution affects survival rate in a murine malaria model.

R Clemens1, H L Bock, B Enders, G Reiner.   

Abstract

The effect of AT III substitution on survival time was studied in P. vinkei infected mice. One hundred mice were infected, randomly selected and allocated to two groups of 40 animals each on day 13 after infection. One group was placebo treated, the other group received 3 IU AT III daily on days 13 to 19. Comparison of the survival time in the log rank test showed a prolongation of the median survival time (5 versus 9 days, P less than 0.01). It is concluded that AT III might be beneficial in the treatment of severe malaria cases.

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Year:  1989        PMID： 2533685     DOI： 10.1007/bf00931069

Source DB:  PubMed          Journal:  Parasitol Res        ISSN： 0932-0113            Impact factor:   2.289


  14 in total

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Journal:  Dtsch Med Wochenschr       Date:  1986-06-13       Impact factor: 0.628

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Authors:  S Looareesuwan; D A Warrell; N J White; P Chanthavanich; M J Warrell; S Chantaratherakitti; S Changswek; L Chongmankongcheep; C Kanchanaranya
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9.  Substitution of antithrombin III in shock and DIC: a randomized study.

Authors:  B Blauhut; H Kramar; H Vinazzer; H Bergmann
Journal:  Thromb Res       Date:  1985-07-01       Impact factor: 3.944

10.  Haemostatic alterations in malaria correlate to parasitaemia.

Authors:  R D Horstmann; M Dietrich
Journal:  Blut       Date:  1985-11
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