Literature DB >> 25336205

Combining DNA methyltransferase and histone deacetylase inhibition to treat acute myeloid leukemia/myelodysplastic syndrome: achievements and challenges.

Michael Lübbert1, Andrea Kuendgen.   

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Year:  2014        PMID: 25336205     DOI: 10.1002/cncr.29083

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


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  11 in total

1.  Phase I study of AR-42 and decitabine in acute myeloid leukemia.

Authors:  Sophia G Liva; Christopher C Coss; Jiang Wang; William Blum; Rebecca Klisovic; Bhavana Bhatnagar; Katherine Walsh; Susan Geyer; Qiuhong Zhao; Ramiro Garzon; Guido Marcucci; Mitch A Phelps; Alison R Walker
Journal:  Leuk Lymphoma       Date:  2020-02-08

2.  Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells.

Authors:  Li Liu; Liang Liu; Lai-Han Leung; Austin J Cooney; Changyi Chen; Todd K Rosengart; Yupo Ma; Jianchang Yang
Journal:  J Biol Chem       Date:  2015-03-03       Impact factor: 5.157

Review 3.  Precision therapy for acute myeloid leukemia.

Authors:  Xue Yang; Jianxiang Wang
Journal:  J Hematol Oncol       Date:  2018-01-05       Impact factor: 17.388

4.  A phase 1b/2b multicenter study of oral panobinostat plus azacitidine in adults with MDS, CMML or AML with ⩽30% blasts.

Authors:  G Garcia-Manero; M A Sekeres; M Egyed; M Breccia; C Graux; J D Cavenagh; H Salman; A Illes; P Fenaux; D J DeAngelo; R Stauder; K Yee; N Zhu; J-H Lee; D Valcarcel; A MacWhannell; Z Borbenyi; L Gazi; S Acharyya; S Ide; M Marker; O G Ottmann
Journal:  Leukemia       Date:  2017-05-26       Impact factor: 11.528

5.  Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia - identification of responders by gene expression profiling of pretreatment leukemic cells.

Authors:  Håkon Reikvam; Randi Hovland; Rakel Brendsdal Forthun; Sigrid Erdal; Bjørn Tore Gjertsen; Hanne Fredly; Øystein Bruserud
Journal:  BMC Cancer       Date:  2017-09-06       Impact factor: 4.430

6.  Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.

Authors:  Chengyin Min; Nathan Moore; Jeffrey R Shearstone; Steven N Quayle; Pengyu Huang; John H van Duzer; Matthew B Jarpe; Simon S Jones; Min Yang
Journal:  PLoS One       Date:  2017-01-06       Impact factor: 3.240

Review 7.  Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid Leukemia.

Authors:  Younguk Sun; Bo-Rui Chen; Aniruddha Deshpande
Journal:  Front Oncol       Date:  2018-02-23       Impact factor: 6.244

8.  Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia.

Authors:  Yunan Li; Mingying Zhang; Mengyao Sheng; Peng Zhang; Zizhen Chen; Wen Xing; Jie Bai; Tao Cheng; Feng-Chun Yang; Yuan Zhou
Journal:  J Cancer Res Clin Oncol       Date:  2018-03-28       Impact factor: 4.553

9.  Biomodulatory Treatment With Azacitidine, All-trans Retinoic Acid and Pioglitazone Induces Differentiation of Primary AML Blasts Into Neutrophil Like Cells Capable of ROS Production and Phagocytosis.

Authors:  Sebastian Klobuch; Tim Steinberg; Emanuele Bruni; Carina Mirbeth; Bernhard Heilmeier; Lina Ghibelli; Wolfgang Herr; Albrecht Reichle; Simone Thomas
Journal:  Front Pharmacol       Date:  2018-11-27       Impact factor: 5.810

Review 10.  Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature.

Authors:  Andrea Kuendgen; Catharina Müller-Thomas; Michael Lauseker; Torsten Haferlach; Petra Urbaniak; Thomas Schroeder; Carolin Brings; Michael Wulfert; Manja Meggendorfer; Barbara Hildebrandt; Beate Betz; Brigitte Royer-Pokora; Norbert Gattermann; Rainer Haas; Ulrich Germing; Katharina S Götze
Journal:  Oncotarget       Date:  2018-06-12
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