Literature DB >> 25336017

R&D productivity rides again?

Dennis Lendrem1, Stephen J Senn, B Clare Lendrem, John D Isaacs.   

Abstract

A recent analysis of R&D productivity suggests that there are grounds for 'cautious optimism' that the industry 'turned the corner' in 2008 and is 'on the comeback trail'. We believe that this analysis is flawed and most probably wrong. We present an alternative analysis of these same data to suggest that the industry is not yet 'out of the woods' and suggest that many of the systemic issues affecting pharmaceutical R&D productivity are still being resolved.
Copyright © 2014 John Wiley & Sons, Ltd.

Entities:  

Keywords:  R&D costs; R&D productivity; costs; development; pharmaceutical industry; pharmaceutical innovation crisis; strategy

Mesh:

Year:  2014        PMID: 25336017     DOI: 10.1002/pst.1653

Source DB:  PubMed          Journal:  Pharm Stat        ISSN: 1539-1604            Impact factor:   1.894


  3 in total

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Authors:  Jaroslaw Polanski; Jacek Bogocz; Aleksandra Tkocz
Journal:  J Comput Aided Mol Des       Date:  2016-04-28       Impact factor: 3.686

2.  Exploratory Analysis of the Factors Associated With Success Rates of Confirmatory Randomized Controlled Trials in Cancer Drug Development.

Authors:  Can Wu; Shunsuke Ono
Journal:  Clin Transl Sci       Date:  2020-08-21       Impact factor: 4.689

Review 3.  Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

Authors:  Ralf-Dieter Hilgers; Malgorzata Bogdan; Carl-Fredrik Burman; Holger Dette; Mats Karlsson; Franz König; Christoph Male; France Mentré; Geert Molenberghs; Stephen Senn
Journal:  Orphanet J Rare Dis       Date:  2018-05-11       Impact factor: 4.123

  3 in total

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