OBJECTIVE: To study the chemical constituents from Laggera pterodonta. METHODS: The compounds were isolated and purified by column chromatographic methods with silica gel, Sephadex LH-20, ODS and preparation HPLC. Their structures were identified by physicochemical properties and spectral data. RESULTS: Ten compounds were isolated and elucidated as 3,4',5-trihydroxy-6,7-dimethoxyflavone (1), 3, 3', 5-trihydroxy-4', 6,7-trimethoxyflavone (2), chrysosplenetin B (3), 5-hydroxy-4', 7-dimethoxyflavanone (4), 5, 7,4'-trihydroxy-3, 3'-dimethoxyflavone (5), artemitin (6), quercetin (7), pinostrobin (8), luteolin (9) and apigenin (10), respectively. CONCLUSION: Compounds 1, 2, 4, 5 and 8 - 10 are isolated from this plant for the first time.
OBJECTIVE: To study the chemical constituents from Laggera pterodonta. METHODS: The compounds were isolated and purified by column chromatographic methods with silica gel, Sephadex LH-20, ODS and preparation HPLC. Their structures were identified by physicochemical properties and spectral data. RESULTS: Ten compounds were isolated and elucidated as 3,4',5-trihydroxy-6,7-dimethoxyflavone (1), 3, 3', 5-trihydroxy-4', 6,7-trimethoxyflavone (2), chrysosplenetin B (3), 5-hydroxy-4', 7-dimethoxyflavanone (4), 5, 7,4'-trihydroxy-3, 3'-dimethoxyflavone (5), artemitin (6), quercetin (7), pinostrobin (8), luteolin (9) and apigenin (10), respectively. CONCLUSION: Compounds 1, 2, 4, 5 and 8 - 10 are isolated from this plant for the first time.