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Literature DB >> 2533411

Changes in maximum expiratory flow-volume curve configuration after treatment with inhaled corticosteroids.

Abstract

The present study reports the changes in configuration of maximal flow-volume curves after eight weeks' treatment with inhaled corticosteroids in 14 asthmatic patients. The configuration was compared with that seen after bronchodilatation following inhalation of a single dose of ipratropium bromide. After inhaled corticosteroids the shape of the flow-volume curves was less bowed toward the volume axis, whereas the shape of the flow-volume curves after inhalation of ipratropium bromide showed no significant change. A significant correlation was observed between the decrease in blood eosinophil cell count and the straightening of the flow-volume curves, quantitatively expressed as shape factor and slope ratio. It is concluded that these changes in flow-volume curve configuration reflect a decrease in inhomogeneously distributed inflammatory airway narrowing.

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Year: 1989 PMID： 2533411 PMCID： PMC1020877 DOI： 10.1136/thx.44.12.1015

Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.139

21 in total

1. Contribution of inhomogeneity of lung units to the maximal expiratory flow-volume curve in children with asthma and cystic fibrosis.

Authors: L I Landau; L M Taussig; P T Macklem; P H Beaudry
Journal: Am Rev Respir Dis Date: 1975-06

2. The pathology of asthma, with special reference to changes in the bronchial mucosa.

Authors: M S DUNNILL
Journal: J Clin Pathol Date: 1960-01 Impact factor: 3.411

3. Wave-speed limitation on expiratory flow-a unifying concept.

Authors: S V Dawson; E A Elliott
Journal: J Appl Physiol Respir Environ Exerc Physiol Date: 1977-09

4. Variability in the maximal expiratory flow volume curve in asymptomatic smokers and in nonsmokers.

Authors: L F Black; K Offord; R E Hyatt
Journal: Am Rev Respir Dis Date: 1974-09

5. Variability of maximum expiratory flow-volume curves.

Authors: M Green; J Mead; J M Turner
Journal: J Appl Physiol Date: 1974-07 Impact factor: 3.531

6. Simplified diagnosis of small-airway obstruction.

Authors: A F Gelb; N Zamel
Journal: N Engl J Med Date: 1973-02-22 Impact factor: 91.245

7. Maximal expiratory flow and total respiratory resistance during induced bronchoconstriction in asthmatic subjects.

Authors: J T Olive; R E Hyatt
Journal: Am Rev Respir Dis Date: 1972-09

8. The maximal expiratory flow-volume curve: its use in the detection of ventilatory abnormalities in a population study.

Authors: R J Knudson; B Burrows; M D Lebowitz
Journal: Am Rev Respir Dis Date: 1976-11

6. Improved spirometric detection of small airway narrowing: concavity in the expiratory flow-volume curve in people aged over 40 years.

Authors: David P Johns; Aruneema Das; Brett G Toelle; Michael J Abramson; Guy B Marks; Richard Wood-Baker; E Haydn Walters
Journal: Int J Chron Obstruct Pulmon Dis Date: 2017-12-13

6 in total

Changes in maximum expiratory flow-volume curve configuration after treatment with inhaled corticosteroids.

1. Contribution of inhomogeneity of lung units to the maximal expiratory flow-volume curve in children with asthma and cystic fibrosis.

2. The pathology of asthma, with special reference to changes in the bronchial mucosa.

3. Wave-speed limitation on expiratory flow-a unifying concept.

4. Variability in the maximal expiratory flow volume curve in asymptomatic smokers and in nonsmokers.

5. Variability of maximum expiratory flow-volume curves.

6. Simplified diagnosis of small-airway obstruction.

7. Maximal expiratory flow and total respiratory resistance during induced bronchoconstriction in asthmatic subjects.

8. The maximal expiratory flow-volume curve: its use in the detection of ventilatory abnormalities in a population study.

9. Analysis of the configuration of maximum expiratory flow-volume curves.

10. Influence of bronchomotor tone on ventilation distribution and airway closure in asymptomatic asthma.

Review 1. Diagnosis and early detection of COPD using spirometry.

2. Effects of time, albuterol, and budesonide on the shape of the flow-volume loop in children with asthma.

3. Application of Machine Learning in Pulmonary Function Assessment Where Are We Now and Where Are We Going?

4. Concave pattern of a maximal expiratory flow-volume curve: a sign of airflow limitation in adult bronchial asthma.

5. Graphic analysis of flow-volume curves: a pilot study.

6. Improved spirometric detection of small airway narrowing: concavity in the expiratory flow-volume curve in people aged over 40 years.