Literature DB >> 25332754

Newborns with congenital heart diseases: epidemiological data from a single reference center in Brazil.

Karina Peres Silva1, Luciane Alves Rocha1, Ana Teresa Figueiredo Stochero Leslie2, Ruth Guinsburg2, Célia Maria Camelo Silva3, Luciano Marcondes Machado Nardozza1, Antonio Fernandes Moron1, Edward Araujo Júnior1.   

Abstract

OBJECTIVE: to describe the epidemiological data of the population born with the diagnosis of Congenital Heart Disease (CHD); to compare diagnoses made using fetal echocardiography with the findings from postnatal echocardiography or anatomopathological examination of the heart; and to evaluate mortality among newborns that underwent surgical treatment.
METHODS: this was a cohort study with information gathered from the medical records of the pregnant women and their newborns diagnosed with CHD during the fetal or postnatal periods, between January 2008 and December 2012. Means, standard deviations and maximum and minimum values were calculated for the quantitative variables. Relative and absolute values were calculated for the qualitative variables. The heart malformations were categorized in four groups: complex lesions, significant lesions, minor lesions and others.
RESULTS: we detected postnatal incidence of CHD of 1.9% at our service. The mean maternal age was 28.3 years and 10 (21.3%) of the pregnant women were ≥ 35 years old. The mean gestational age at the time of performing the fetal echocardiogram was 27.8 weeks. Mean gestational age at delivery was 38 weeks, and the mean weight of the newborns was 2,644.5 grams. Regarding the diagnosis of CHD, there were: 23 complex lesions (39%); 15 significant lesions (26%); 10 minor lesions (17%); 4 other lesions (7%) and 6 normal anatomies (10%). The diagnosis of CHD made on the fetus and postnatally coincided in 77.6% of the cases. A total of 27 patients (60%) underwent surgery, and the outcome was neonatal death in five cases.
CONCLUSION: we detected postnatal incidence of CHD of 1.9%, and it was more common among older pregnant women and with late detection in the intrauterine period. Complex heart diseases predominated, thus making it difficult to have a good result regarding neonatal mortality rates.

Entities:  

Keywords:  congenital heart diseases; echocardiography; newborn; prenatal diagnosis

Year:  2014        PMID: 25332754      PMCID: PMC4186997     

Source DB:  PubMed          Journal:  J Prenat Med        ISSN: 1971-3282


  20 in total

1.  The results of fetal echocardiography in a tertiary center and comparison of low- and high-risk pregnancies for fetal congenital heart defects.

Authors:  Süheyla Ozkutlu; Tülay Akça; Gülden Kafali; Sinan Beksaç
Journal:  Anadolu Kardiyol Derg       Date:  2010-06

2.  Spatio-temporal image correlation (STIC) used by general obstetricians is marginally clinically effective compared to 2D fetal echocardiography scanning by experts.

Authors:  Prapat Wanitpongpan; Takeshi Kanagawa; Yukiko Kinugasa; Tadashi Kimura
Journal:  Prenat Diagn       Date:  2008-10       Impact factor: 3.050

3.  Congenital heart disease in a Chinese hospital: pre- and postnatal detection, incidence, clinical characteristics and outcomes.

Authors:  Zhangbin Yu; Yangyang Xi; Wenxiao Ding; Shuping Han; Li Cao; Chun Zhu; Xuejie Wang; Xirong Guo
Journal:  Pediatr Int       Date:  2011-10-30       Impact factor: 1.524

4.  Audit of 10 years of referrals for fetal echocardiography.

Authors:  S A B Clur; P M Van Brussel; I B Mathijssen; E Pajkrt; J Ottenkamp; C M Bilardo
Journal:  Prenat Diagn       Date:  2011-09-14       Impact factor: 3.050

5.  Accuracy of four-dimensional spatiotemporal image correlation echocardiography in the prenatal diagnosis of congenital heart defects.

Authors:  M Bennasar; J M Martínez; O Gómez; J Bartrons; A Olivella; B Puerto; E Gratacós
Journal:  Ultrasound Obstet Gynecol       Date:  2010-10       Impact factor: 7.299

Review 6.  Incidence of congenital heart disease: II. Prenatal incidence.

Authors:  J I Hoffman
Journal:  Pediatr Cardiol       Date:  1995 Jul-Aug       Impact factor: 1.655

7.  Prenatal diagnosis of congenital heart disease in the northern region of England: benefits of a training programme for obstetric ultrasonographers.

Authors:  S Hunter; A Heads; J Wyllie; S Robson
Journal:  Heart       Date:  2000-09       Impact factor: 5.994

8.  Temporal variability in birth prevalence of cardiovascular malformations.

Authors:  C Wren; S Richmond; L Donaldson
Journal:  Heart       Date:  2000-04       Impact factor: 5.994

Review 9.  Prenatal diagnosis of structural cardiac defects.

Authors:  Lindsey Allan
Journal:  Am J Med Genet C Semin Med Genet       Date:  2007-02-15       Impact factor: 3.908

10.  Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registries.

Authors:  E Garne; C Stoll; M Clementi
Journal:  Ultrasound Obstet Gynecol       Date:  2001-05       Impact factor: 7.299

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  1 in total

1.  An artificial neural network prediction model of congenital heart disease based on risk factors: A hospital-based case-control study.

Authors:  Huixia Li; Miyang Luo; Jianfei Zheng; Jiayou Luo; Rong Zeng; Na Feng; Qiyun Du; Junqun Fang
Journal:  Medicine (Baltimore)       Date:  2017-02       Impact factor: 1.889

  1 in total

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