Literature DB >> 25332733

A sample-to-result system for blood coagulation tests on a microfluidic disk analyzer.

Chia-Hui Lin1, Cheng-Yuan Liu2, Chih-Hsin Shih2, Chien-Hsing Lu.   

Abstract

In this report, we describe in detail a microfluidic analyzer, which is able to conduct blood coagulation tests using whole blood samples. Sample preparation steps, such as whole blood aliquoting and metering, plasma separation, decanting, and mixing with reagents were performed in sequence through microfluidic functions integrated on a disk. Both prothrombin time (PT) and activated partial thromboplastin time (aPTT) were carried out on the same platform and the test results can be reported in 5 min. Fifty clinical samples were tested for both PT and aPTT utilizing the microfluidic disk analyzer and the instrument used in hospitals. The test results showed good correlation and agreement between the two instruments.

Entities:  

Year:  2014        PMID： 25332733      PMCID： PMC4189420          DOI： 10.1063/1.4893917

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN： 1932-1058            Impact factor:   2.800


  18 in total

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2.  Batch-mode mixing on centrifugal microfluidic platforms.

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3.  A fully integrated prothrombin time test on the microfluidic disk analyzer.

Authors:  Chia-Hui Lin; Chih-Hsin Shih; Chien-Hsing Lu
Journal:  J Nanosci Nanotechnol       Date:  2013-03

4.  Effect of clot-detection methods and reagents on activated partial thromboplastin time (APTT). Implications in heparin monitoring by APTT.

Authors:  A D'Angelo; M P Seveso; S V D'Angelo; F Gilardoni; A G Dettori; P Bonini
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5.  A portable centrifugal analyser for liver function screening.

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Journal:  Biosens Bioelectron       Date:  2014-01-27       Impact factor: 10.618

6.  Point of care and central laboratory determinations of the aPTT are not interchangeable in surgical intensive care patients.

Authors:  M Ferring; G Reber; P de Moerloose; P Merlani; M Diby; B Ricou
Journal:  Can J Anaesth       Date:  2001-12       Impact factor: 5.063

7.  The responsiveness of different APTT reagents to mild factor VIII, IX and XI deficiencies.

Authors:  A Bowyer; S Kitchen; M Makris
Journal:  Int J Lab Hematol       Date:  2010-09-14       Impact factor: 2.877

8.  Canadian atrial fibrillation anticoagulation study: were the patients subsequently treated with warfarin? Canadian Atrial Fibrillation Anticoagulation Study Group.

Authors:  A Laupacis; K Sullivan
Journal:  CMAJ       Date:  1996-06-01       Impact factor: 8.262

9.  A fully automated immunoassay from whole blood on a disc.

Authors:  Beom Seok Lee; Jung-Nam Lee; Jong-Myeon Park; Jeong-Gun Lee; Suhyeon Kim; Yoon-Kyoung Cho; Christopher Ko
Journal:  Lab Chip       Date:  2009-03-05       Impact factor: 6.799

Review 10.  Use of warfarin in long-term care: a systematic review.

Authors:  Marjorie Neidecker; Aarti A Patel; Winnie W Nelson; Gregory Reardon
Journal:  BMC Geriatr       Date:  2012-04-05       Impact factor: 3.921
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  7 in total

1.  On-chip recalcification of citrated whole blood using a microfluidic herringbone mixer.

Authors:  Marcus Lehmann; Alison M Wallbank; Kimberly A Dennis; Adam R Wufsus; Kara M Davis; Kuldeepsinh Rana; Keith B Neeves
Journal:  Biomicrofluidics       Date:  2015-11-18       Impact factor: 2.800

2.  Preface to Special Topic: Selected Papers from the Advances in Microfluidics and Nanofluidics 2014 Conference in Honor of Professor Hsueh-Chia Chang's 60th Birthday.

Authors:  Chia-Fu Chou; Pei-Kuen Wei; Yeng-Long Chen
Journal:  Biomicrofluidics       Date:  2014-10-28       Impact factor: 2.800

3.  Engineering a simple lateral flow device for animal blood coagulation monitoring.

Authors:  Hua Li; Daewoo Han; Giovanni M Pauletti; Andrew J Steckl
Journal:  Biomicrofluidics       Date:  2018-01-23       Impact factor: 2.800

4.  A droplet-based microfluidic viscometer for the measurement of blood coagulation.

Authors:  Sarah E Mena; Yunzi Li; Joseph McCormick; Brendan McCracken; Carmen Colmenero; Kevin Ward; Mark A Burns
Journal:  Biomicrofluidics       Date:  2020-01-17       Impact factor: 2.800

5.  The centrifugal viscometer.

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Journal:  Biomicrofluidics       Date:  2021-09-01       Impact factor: 3.258

Review 6.  Evolving Paradigm of Prothrombin Time Diagnostics with Its Growing Clinical Relevance towards Cardio-Compromised and COVID-19 Affected Population.

Authors:  Anubhuti Saha; Ashutosh Bajpai; Vinay Krishna; Shantanu Bhattacharya
Journal:  Sensors (Basel)       Date:  2021-04-09       Impact factor: 3.576

Review 7.  Microfluidic devices for studying coagulation biology.

Authors:  Brady M Trevisan; Christopher D Porada; Anthony Atala; Graça Almeida-Porada
Journal:  Semin Cell Dev Biol       Date:  2020-06-18       Impact factor: 7.499
  7 in total

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