Literature DB >> 25332614

A Case of Early Ocular Manifestation of Maculopathy in a 37 year Old Male Patient of CLL.

Syed Riaz Mehdi1, Nishi Tandon2, Sufia Ahmad Khan2, Sharique Ahmad2.   

Abstract

B cell chronic lymphocytic leukemia (CLL) also called chronic lymphocytic leukemia is a disease of elderly, but in rare cases it can occur in young adults. Majority of patients present with no specific symptoms, and CLL is suspected on the basis of high total and relative lymphocyte counts, discovered on routine blood examination. This patient was referred from medicine outpatient in our institute, Era's Lucknow Medical College & Hospital for routine complete blood count. His total leukocyte count came out to be alarmingly high. The general blood picture and bone marrow examinations were consistent with CLL. On immunophenotyping CD5 and CD23 were positive. His cervical lymph nodes biopsy was reported as a case of CLL/small lymphocytic lymphoma. On his complaint of hazy vision his funduscopy revealed maculopathy. This makes our case a unique and rare one, as maculopathy in a young patient of CLL has not yet been reported from India.

Entities:  

Keywords:  Chronic lymphocytic leukemia (CLL); Maculopathy; Small lymphocytic lymphoma (SLL); Young adults

Year:  2014        PMID: 25332614      PMCID: PMC4192171          DOI: 10.1007/s12288-014-0399-8

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  5 in total

1.  Retinal complications associated with hyperviscosity in chronic lymphocytic leukaemia.

Authors:  C E F Davies; R A F Whitelocke; S Agrawal
Journal:  Intern Med J       Date:  2008-02       Impact factor: 2.048

Review 2.  Recent advances in chronic lymphocytic leukemia.

Authors:  N Vyas; A Hassan
Journal:  Indian J Cancer       Date:  2012 Jan-Mar       Impact factor: 1.224

3.  Chronic lymphocytic leukemia in young adults.

Authors:  C M Spier; C R Kjeldsberg; D R Head; K C DiFiore; B Tudor
Journal:  Am J Clin Pathol       Date:  1985-11       Impact factor: 2.493

4.  Ophthalmic manifestations, cytology, immunohistochemistry, and molecular analysis of intraocular metastatic T-cell lymphoma: report of a case and review of the literature.

Authors:  Grace A Levy-Clarke; David Greenman; Pamela C Sieving; Gordon Byrnes; Defen Shen; Robert Nussenblatt; Chi-Chao Chan
Journal:  Surv Ophthalmol       Date:  2008 May-Jun       Impact factor: 6.048

5.  Ocular involvement as the initial manifestation of T-cell chronic lymphocytic leukemia.

Authors:  Carmen J Calfa; Izidore S Lossos; Phillip Ruiz; Janet L Davis
Journal:  Am J Ophthalmol       Date:  2007-08       Impact factor: 5.258

  5 in total

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