Literature DB >> 25332574

A Case of AML-M2 with Sole Interstitial Deletion in 9q Without AML1-ETO/Inv 16 Rearrangement and FLT3/NPMI Mutations.

G Sandhya Devi1, Faiq Ahmed1, Manasi C Mundada1, S Sudha Murthy1, Krishna Mohan Mallavarapu2.   

Abstract

Conventional/molecular cytogenetics is important in identification of genomic abnormalities, for prognostication and in risk stratification of de novo patients with acute myeloid leukemias (AML). Here we present an AML M2 case showing the sole karyotypic abnormality, the rare interstitial deletion in the long arm of chromosome 9 with the loss of segment q12-q13.

Entities:  

Keywords:  AML-M2; CD7; Conventional cytogenetics; Del 9q

Year:  2014        PMID： 25332574      PMCID： PMC4192194          DOI： 10.1007/s12288-013-0322-8

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  9 in total

1.  Del (9q) AML: clinical and cytological characteristics and prognostic implications.

Authors:  Andrew Peniket; James Wainscoat; Lucy Side; Sarah Daly; Rajko Kusec; Georgina Buck; Keith Wheatley; Helen Walker; Steve Chatters; Christine Harrison; Jacqueline Boultwood; Anthony Goldstone; Alan Burnett
Journal:  Br J Haematol       Date:  2005-04       Impact factor: 6.998

2.  Interstitial deletion of 9q in a case of acute myeloid leukemia with t(8;21).

Authors:  B Kar; K G Dhanalakshmi; R Revathi
Journal:  Indian J Hematol Blood Transfus       Date:  2008-08-24       Impact factor: 0.900

3.  Delineation of the minimal commonly deleted segment and identification of candidate tumor-suppressor genes in del(9q) acute myeloid leukemia.

Authors:  David A Sweetser; Andrew J Peniket; Christina Haaland; Adam A Blomberg; Yuntian Zhang; Syed Tanweer Zaidi; Farshid Dayyani; Zheng Zhao; Nyla A Heerema; Jacqueline Boultwood; Gordon W Dewald; Elisabeth Paietta; Marilyn L Slovak; Cheryl L Willman; James S Wainscoat; Irwin D Bernstein; Sarah B Daly
Journal:  Genes Chromosomes Cancer       Date:  2005-11       Impact factor: 5.006

4.  Acute myeloid leukemia with deletion 9q within a noncomplex karyotype is associated with CEBPA loss-of-function mutations.

Authors:  Stefan Fröhling; Richard F Schlenk; Jürgen Krauter; Christian Thiede; Gerhard Ehninger; Detlef Haase; Lana Harder; Sylvia Kreitmeier; Claudia Scholl; Michael A Caligiuri; Clara D Bloomfield; Hartmut Döhner; Konstanze Döhner
Journal:  Genes Chromosomes Cancer       Date:  2005-04       Impact factor: 5.006

Review 5.  The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes.

Authors:  James W Vardiman; Jüergen Thiele; Daniel A Arber; Richard D Brunning; Michael J Borowitz; Anna Porwit; Nancy Lee Harris; Michelle M Le Beau; Eva Hellström-Lindberg; Ayalew Tefferi; Clara D Bloomfield
Journal:  Blood       Date:  2009-04-08       Impact factor: 22.113

6.  Specific chromosomal aberrations in de novo acute myeloid leukemia: a comparative analysis of results with a report of three novel chromosomal rearrangements t(7;14)(q35;q13), t(8;18)(p11.2;q12), t(13;15) in Indian population.

Authors:  Firoz Ahmad; Rupa Dalvi; Bibhu Ranjan Das; Swarna Mandava
Journal:  Cancer Detect Prev       Date:  2008-07-18

7.  Nucleophosmin mutation in Southeast Asian acute myeloid leukemia: eight novel variants, FLT3 coexistence and prognostic impact of NPM1/FLT3 mutations.

Authors:  Chetsada Boonthimat; Wanna Thongnoppakhun; Chirayu U Auewarakul
Journal:  Haematologica       Date:  2008-07-18       Impact factor: 9.941

8.  Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.

Authors:  Farshid Dayyani; Jianfeng Wang; Jing-Ruey J Yeh; Eun-Young Ahn; Erica Tobey; Dong-Er Zhang; Irwin D Bernstein; Randall T Peterson; David A Sweetser
Journal:  Blood       Date:  2008-02-07       Impact factor: 22.113

9.  Acute myeloid leukemia with the t(8;21) translocation: clinical consequences and biological implications.

Authors:  Håkon Reikvam; Kimberley Joanne Hatfield; Astrid Olsnes Kittang; Randi Hovland; Øystein Bruserud
Journal:  J Biomed Biotechnol       Date:  2011-05-03
  9 in total

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