Literature DB >> 25332573

Looking beyond the obvious: an unusual cause of iron deficiency anaemia.

C S Jyotirmanju1, P Mallya1, Aarthi Rau2, A T K Rau1.   

Abstract

Iron deficiency anaemia (IDA) is the most common haematological disorder seen in childhood. While poor intake of iron is the most common cause of IDA, a diligent search must be made to exclude other causes. We present a 5 year old girl who had recurrent hospital admissions for chest infection, radiographic evidence of bilateral pulmonary infiltrates and severe IDA. When she failed to respond to repeated courses of antibiotics, anti tubercular and parenteral and oral iron therapy, a lung biopsy was done which revealed blood and hemosiderophages within the alveoli. Further investigations were suggestive of SLE (dsDNA positivity). A diagnosis of SLE induced alveolar haemorrhage was made and therapy with glucocorticoids was initiated. She has responded well to therapy.

Entities:  

Keywords:  Diffuse alveolar hemorrhage (DAH); Iron deficiency anemia IDA; Pulmonary hemosiderosis; Systemic lupus erythematosus (SLE)

Year:  2014        PMID: 25332573      PMCID: PMC4192227          DOI: 10.1007/s12288-013-0321-9

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  16 in total

Review 1.  Diffuse alveolar hemorrhage.

Authors:  Abigail R Lara; Marvin I Schwarz
Journal:  Chest       Date:  2010-05       Impact factor: 9.410

2.  Idiopathic pulmonary haemosiderosis in Japan: 39 possible cases from a survey questionnaire.

Authors:  S Ohga; K Takahashi; S Miyazaki; H Kato; K Ueda
Journal:  Eur J Pediatr       Date:  1995-12       Impact factor: 3.183

3.  Anemia as the sole presenting symptom of idiopathic pulmonary hemosiderosis: report of two cases.

Authors:  Kao-Chun Chen; Chih-Cheng Hsiao; Shun-Chen Huang; Sheung-Fat Ko; Chen-Kuang Niu
Journal:  Chang Gung Med J       Date:  2004-11

4.  Clinical spectrum associated with ANCA of defined antigen specificities in 98 selected patients.

Authors:  C Geffriaud-Ricouard; L H Noël; D Chauveau; S Houhou; J P Grünfeld; P Lesavre
Journal:  Clin Nephrol       Date:  1993-03       Impact factor: 0.975

Review 5.  Diffuse alveolar hemorrhage.

Authors:  Harold R Collard; Marvin I Schwarz
Journal:  Clin Chest Med       Date:  2004-09       Impact factor: 2.878

6.  Immunosuppression and plasma-exchange in the treatment of Goodpasture's syndrome.

Authors:  C M Lockwood; A J Rees; T A Pearson; D J Evans; D K Peters; C B Wilson
Journal:  Lancet       Date:  1976-04-03       Impact factor: 79.321

7.  Decade long unexplained anemia: alert to ANCA associated vasculitis.

Authors:  Vidushi Mahajan; Kanaram Jat; Suman Kochhar; Sanjay D'Cruz
Journal:  Indian Pediatr       Date:  2013-02       Impact factor: 1.411

8.  Pulmonary lesions in childhood onset systemic lupus erythematosus: analysis of 26 cases, and summary of literature.

Authors:  R L Nadorra; B H Landing
Journal:  Pediatr Pathol       Date:  1987

Review 9.  Idiopathic pulmonary haemosiderosis revisited.

Authors:  O C Ioachimescu; S Sieber; A Kotch
Journal:  Eur Respir J       Date:  2004-07       Impact factor: 16.671

10.  Idiopathic pulmonary hemosiderosis in a 9-year-old girl.

Authors:  E Kamienska; T Urasinski; A Gawlikowska-Sroka; B Glura; A Pogorzelski
Journal:  Eur J Med Res       Date:  2009-12-07       Impact factor: 2.175

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