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Literature DB >> 25332547

Symptomatic Acquired Haemophilia Due to Circulating Antibodies Against Both Factor VIII and IX in a Non-haemophiliac Patient.

Sharat Damodar¹, Prashantha Bhat¹, Sitalakshmi Balasubramaniam².

Abstract

Acquired haemophilia is a very rare condition, occurring in less than 2 per million populations. This condition is caused commonly by acquired antibodies against factor VIII and rarely by antibodies against factor IX. Here we describe an extremely rare presentation of idiopathic acquired haemophilia in an otherwise healthy male patient, caused by simultaneous occurrence of circulating antibodies against both factor VIII and IX.

Entities: Disease Species

Keywords: Acquired haemophilia; Factor IX inhibitor; Factor VIII inhibitor

Year: 2013 PMID： 25332547 PMCID： PMC4192245 DOI： 10.1007/s12288-013-0270-3

Source DB: PubMed Journal: Indian J Hematol Blood Transfus ISSN： 0971-4502 Impact factor: 0.900

11 in total

Review 1. Acquired haemophilia: review and meta-analysis focused on therapy and prognostic factors.

Authors: Julio Delgado; Victor Jimenez-Yuste; Fernando Hernandez-Navarro; Ana Villar
Journal: Br J Haematol Date: 2003-04 Impact factor: 6.998

2. Combined factor VIII and IX inhibitors in a non-haemophilic patient: successful treatment with immunosuppressive drugs.

Authors: F Carmassi; C Giannarelli; A De Giorgi; F De Negri
Journal: Haemophilia Date: 2007-01 Impact factor: 4.287

3. Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation.

Authors: Peter W Collins; Sybil Hirsch; Trevor P Baglin; Gerard Dolan; John Hanley; Michael Makris; David M Keeling; Ri Liesner; Simon A Brown; Charles R M Hay
Journal: Blood Date: 2006-10-17 Impact factor: 22.113

Symptomatic Acquired Haemophilia Due to Circulating Antibodies Against Both Factor VIII and IX in a Non-haemophiliac Patient.

Review 1. Acquired haemophilia: review and meta-analysis focused on therapy and prognostic factors.

2. Combined factor VIII and IX inhibitors in a non-haemophilic patient: successful treatment with immunosuppressive drugs.

3. Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation.

4. Inhibitors of factors VIII and IX in a child with Henoch-Schönlein syndrome.

Review 5. [Acquired haemophilia B: a case report and literature review].

6. Combined factor VIII and IX inhibitors in a girl.

7. Circulating IgG antibodies against factors IX and VIII in multiple sclerosis.

8. Use of porcine factor VIII in the treatment of patients with acquired hemophilia.

9. A survey of 215 non-hemophilic patients with inhibitors to Factor VIII.

10. International recommendations on the diagnosis and treatment of patients with acquired hemophilia A.

1. Acquired Hemophilia A: Experience of a Tertiary Care Institute from North India.