Literature DB >> 2533149

Review of the endocrine actions of luteinising hormone-releasing hormone analogues in premenopausal women with breast cancer.

R I Nicholson1, K J Walker, R F Walker, G F Read, A Turkes, J F Robertson, R W Blamey.   

Abstract

The endocrinological actions of the luteinising hormone-releasing hormone (LHRH) analogue, Zoladex (goserelin) in premenopausal women with advanced breast cancer are reviewed. LHRH analogues are an interesting addition to the currently available treatments for hormone-sensitive breast cancer in premenopausal women. Their modest side effects and ease of administration are in contrast to the risks and morbidity of surgical endocrine therapy.

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Year:  1989        PMID： 2533149     DOI： 10.1159/000181345

Source DB:  PubMed          Journal:  Horm Res        ISSN： 0301-0163


  5 in total

Review 1.  Complete estrogen blockade for the treatment of metastatic and early stage breast cancer.

Authors:  L B Michaud; A U Buzdar
Journal:  Drugs Aging       Date:  2000-04       Impact factor: 3.923

2.  Growth inhibition of estrogen independent MXT mouse mammary carcinomas in mice treated with an agonist or antagonist of LH-RH, an analog of somatostatin, or a combination.

Authors:  K Szepeshazi; S Milovanovic; K Lapis; K Groot; A V Schally
Journal:  Breast Cancer Res Treat       Date:  1992       Impact factor: 4.872

3.  Short-chain analogs of luteinizing hormone-releasing hormone containing cytotoxic moieties.

Authors:  T Janáky; A Juhász; Z Rékási; P Serfözö; J Pinski; L Bokser; G Srkalovic; S Milovanovic; T W Redding; G Halmos
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

4.  Evaluation of binding of cytotoxic analogs of luteinizing hormone-releasing hormone to human breast cancer and mouse MXT mammary tumor.

Authors:  S R Milovanovic; S Radulovic; A V Schally
Journal:  Breast Cancer Res Treat       Date:  1992       Impact factor: 4.872

5.  Effect of treatment with LHRH analogs containing cytotoxic radicals on the binding characteristics of receptors for luteinizing-hormone-releasing hormone in MXT mouse mammary carcinoma.

Authors:  S R Milovanovic; E Monje; K Szepeshazi; S Radulovic; A Schally
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553
  5 in total

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