Literature DB >> 25330952

Consider benign Müllerian papilloma: a rare cause of vaginal bleeding in children.

Venkat Yalamanchili1, Pouya Entezami, Scott Langenburg, Paul Stockmann.   

Abstract

Vaginal bleeding in young girls is a distressing symptom. Due to the potential for malignancy, thorough investigation is needed. Though rare, Müllerian papillomas are a benign cause of such symptoms. We report the case of a 2-year-old female who presented with acute onset of vaginal bleeding. She had another episode of bleeding during admission and was taken to the operating room for vaginoscopy under general anesthesia. A single friable lesion with active bleeding was visualized near the anterior vagina or cervix, which was biopsied. Histopathologic examination demonstrated characteristic features of benign Müllerian papilloma of infancy. Müllerian papillomas require examination under anesthesia and vaginoscopy with biopsies for efficient and accurate diagnosis. Treatment consists of complete local excision. Local recurrences are not uncommon, though prognosis for primary or recurrent disease is excellent.

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Year:  2014        PMID: 25330952     DOI: 10.1007/s00383-014-3630-7

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  15 in total

1.  Pigmented müllerian papilloma of the vagina.

Authors:  M Cohen; L Pedemonte; R Drut
Journal:  Histopathology       Date:  2001-11       Impact factor: 5.087

2.  Malignant progression through borderline changes in recurrent Mullerian papilloma of the vagina.

Authors:  J Abu; D Nunns; D Ireland; L Brown
Journal:  Histopathology       Date:  2003-05       Impact factor: 5.087

3.  Benign müllerian papilloma of childhood.

Authors:  Gary W Mierau; Mark A Lovell; Josephine Wyatt-Ashmead; Luann Goin
Journal:  Ultrastruct Pathol       Date:  2005 May-Aug       Impact factor: 1.094

4.  Benign müllerian papilloma of the cervix.

Authors:  Atul Kumar; Alka Kumar
Journal:  J Minim Invasive Gynecol       Date:  2012 Sep-Oct       Impact factor: 4.137

5.  Borderline malignant change in recurrent müllerian papilloma of the vagina.

Authors:  S P Dobbs; P A Shaw; L J Brown; D Ireland
Journal:  J Clin Pathol       Date:  1998-11       Impact factor: 3.411

6.  Müllerian papilloma of the cervix in a child with multiple renal cysts.

Authors:  Brian R Lane; Jonathan H Ross; William R Hart; Robert Kay
Journal:  Urology       Date:  2005-02       Impact factor: 2.649

Review 7.  Benign papilloma of the cervix in childhood: immunohistochemical findings and review of the literature.

Authors:  A Schmedding; M Zense; J Fuchs; S Glüer
Journal:  Eur J Pediatr       Date:  1997-04       Impact factor: 3.183

8.  The aetiology of vaginal bleeding in children. A 20-year review.

Authors:  N C Hill; L W Oppenheimer; K E Morton
Journal:  Br J Obstet Gynaecol       Date:  1989-04

9.  Vaginal Müllerian papilloma in a 2-year-old child.

Authors:  Elisangela Arbo; Ricardo dos Reis; Diego Uchoa; Solange Garcia Acetta; Waldemar Augusto Rivoire; Edison Capp
Journal:  Gynecol Obstet Invest       Date:  2004-05-12       Impact factor: 2.031

10.  Vaginal müllerian papilloma: an unusual cause of vaginal bleeding in a toddler.

Authors:  Carlos A Reck-Burneo; Jocelyn Villanueva; Francisca T Velcek
Journal:  J Pediatr Adolesc Gynecol       Date:  2009-07-17       Impact factor: 1.814

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