Literature DB >> 25329757

A novel aggregation-induced emission based fluorescent probe for an angiotensin converting enzyme (ACE) assay and inhibitor screening.

Haibo Wang1, Yi Huang, Xiaoping Zhao, Wan Gong, Yi Wang, Yiyu Cheng.   

Abstract

A 'turn-on' fluorescent probe based on aggregation-induced emission (AIE) has been developed. It exhibits excellent selectivity and sensitivity for monitoring angiotensin converting enzyme (ACE) activity both in solutions and in living cells as well as for screening ACE inhibitors in vitro.

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Year:  2014        PMID： 25329757     DOI： 10.1039/c4cc07161a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe.

Authors:  Zhenzhong Yang; Jun Li; Xuechun Chen; Xiaoping Zhao; Yi Wang
Journal:  J Pharm Anal       Date:  2020-11-28

2.  A novel biocompatible zwitterionic polyurethane with AIE effect for cell imaging in living cells.

Authors:  Junhuai Xu; Rui Yan; Haibo Wang; Zongliang Du; Jun Gu; Xu Cheng; Junjie Xiong
Journal:  RSC Adv       Date:  2018-02-12       Impact factor: 4.036

3.  Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.

Authors:  Yitian Zhou; Gabriel Herras Arribas; Ainoleena Turku; Tuuli Jürgenson; Souren Mkrtchian; Kristi Krebs; Yi Wang; Barbora Svobodova; Lili Milani; Gunnar Schulte; Jan Korabecny; Stefano Gastaldello; Volker M Lauschke
Journal:  Sci Adv       Date:  2021-09-01       Impact factor: 14.136

Review 4.  Peptide-drug conjugates as effective prodrug strategies for targeted delivery.

Authors:  Yin Wang; Andrew G Cheetham; Garren Angacian; Hao Su; Lisi Xie; Honggang Cui
Journal:  Adv Drug Deliv Rev       Date:  2016-06-29       Impact factor: 15.470
  4 in total

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