| Literature DB >> 25329642 |
Jory Lietard1, Matthew R Hassler, Johans Fakhoury, Masad J Damha.
Abstract
The preparation of a polystyrene solid support decorated with a photolabile linker is described. The entire post-synthetic processing of RNA can be carried out in the solid phase in a minimum amount of time. The deprotected RNA is available for "on-support" hybridization and photolysis releases siRNA duplexes under mild, neutral conditions.Entities:
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Year: 2014 PMID： 25329642 DOI： 10.1039/c4cc07153k
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222