Literature DB >> 25327260

MMP-2 responsive polymeric micelles for cancer-targeted intracellular drug delivery.

Wei-Hai Chen1, Guo-Feng Luo, Qi Lei, Hui-Zhen Jia, Sheng Hong, Qing-Rong Wang, Ren-Xi Zhuo, Xian-Zheng Zhang.   

Abstract

Multifunctional Biotin-PEG-b-PLL(Mal)-peptide-DOX polymeric micelles were prepared to selectively eliminate cancer cells. The micelles were able to enhance cancer cell uptake via the receptor-mediated endocytosis and respond to the stimulus of cancer cell excessive secreted protease MMP-2 to release the anticancer drug and induce apoptosis of cancer cells in a targeted manner.

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Year:  2014        PMID： 25327260     DOI： 10.1039/c4cc07563c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Tumor Microenvironmental Responsive Liposomes Simultaneously Encapsulating Biological and Chemotherapeutic Drugs for Enhancing Antitumor Efficacy of NSCLC.

Authors:  Liang Kong; Shi-Meng Zhang; Jia-Hao Chu; Xin-Ze Liu; Lu Zhang; Si-Yu He; Si-Min Yang; Rui-Jun Ju; Xue-Tao Li
Journal:  Int J Nanomedicine       Date:  2020-08-25

Review 2.  Stimuli-responsive nanoparticles for targeting the tumor microenvironment.

Authors:  Jinzhi Du; Lucas A Lane; Shuming Nie
Journal:  J Control Release       Date:  2015-09-01       Impact factor: 9.776

3.  Antimicrobial peptide-modified silver nanoparticles for enhancing the antibacterial efficacy.

Authors:  Wenxi Li; Yongchun Li; Pengchao Sun; Nan Zhang; Yidan Zhao; Shangshang Qin; Yongxing Zhao
Journal:  RSC Adv       Date:  2020-10-22       Impact factor: 4.036

Review 4.  Mesoporous silica nanoparticles for stimuli-responsive controlled drug delivery: advances, challenges, and outlook.

Authors:  Yuanhui Song; Yihong Li; Qien Xu; Zhe Liu
Journal:  Int J Nanomedicine       Date:  2016-12-20

Review 5.  Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment.

Authors:  Binlong Chen; Wenbing Dai; Bing He; Hua Zhang; Xueqing Wang; Yiguang Wang; Qiang Zhang
Journal:  Theranostics       Date:  2017-01-07       Impact factor: 11.556

Review 6.  Stimuli-responsive polymeric micelles for drug delivery and cancer therapy.

Authors:  Qing Zhou; Li Zhang; TieHong Yang; Hong Wu
Journal:  Int J Nanomedicine       Date:  2018-05-18

7.  Dual-Responsive Core Crosslinking Glycopolymer-Drug Conjugates Nanoparticles for Precise Hepatocarcinoma Therapy.

Authors:  Jing Wu; Jiayi Yuan; Baotong Ye; Yaling Wu; Zheng Xu; Jinghua Chen; Jingxiao Chen
Journal:  Front Pharmacol       Date:  2018-07-17       Impact factor: 5.810

8.  Photosensitive Supramolecular Micelle-Mediated Cellular Uptake of Anticancer Drugs Enhances the Efficiency of Chemotherapy.

Authors:  Yihalem Abebe Alemayehu; Wen-Lu Fan; Fasih Bintang Ilhami; Chih-Wei Chiu; Duu-Jong Lee; Chih-Chia Cheng
Journal:  Int J Mol Sci       Date:  2020-06-30       Impact factor: 5.923
  8 in total

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