Literature DB >> 25326766

Osteochondral transplantation of autologous graft for the treatment of osteochondral lesions of talus: 5- to 7-year follow-up.

Dimitrios Georgiannos1,2, Ilias Bisbinas3, Athanasios Badekas4.   

Abstract

PURPOSE: Bone marrow stimulation procedures (microfractures/drilling) are considered the gold standard for the primary treatment of osteochondral talar lesions. In the literature, there is lack of evidence about the appropriate treatment in cases of failure of these procedures. A technique of osteochondral autologous transplantation of talar graft was used. It was hypothesized that this is a successful method with good results and low complication rates. Additionally, a technique of anterior ankle approach with temporary removal of a bone block from the distal tibia that gives adequate access to posterior talar dome lesions is demonstrated.
METHODS: Between 2004 and 2007, 46 patients (37 males, 9 females), with OLT for which arthroscopic treatment with curettage and drilling or microfracture had failed, underwent osteochondral transplantation with an osteochondral graft harvested from the ipsilateral talar articular facet. A medial malleolar osteotomy or a distal tibial wedge osteotomy was used to access the talar dome defect.
RESULTS: The median follow-up time was 5.5 years (range 52-75 m). Thirty-four lesions (70.8 %) were located in the central talar dome in the coronal plane, while 26 (54.1 %) and 19 (39.5 %) lesions were located in the lateral and medial aspect of talar dome in saggital plane, respectively. The overall improvement between the preoperative and post-operative AOFAS and VAS FA score was 35 points (p < 0.001) and 39 points (p < 0.001), respectively. Clinical results were considered as good in 43 patients (93.4 %) and fair in three patients (6.5 %). All the transplanted grafts were observed to incorporate fully into the recipient bed. No complications occurred at the site of the malleolus osteotomy or tibial osteotomy and the donor site at the talus.
CONCLUSIONS: The midterm results suggest that the technique of osteochondral transplantation of autologous talar graft for osteochondral lesions of talus after failure of primary treatment with bone marrow stimulation can be safely and successfully used. It demonstrates excellent post-operative scores including improvement of pain and function. This procedure is combined with removal of a tibial bone block and its subsequent replacement and does not yield complications experienced with other procedures. LEVEL OF EVIDENCE: Retrospective case series, Level IV.

Entities:  

Keywords:  Autologous cartilaginous graft; Osteochondral lesion of talus (OLT); Osteochondral talar defect (OCD); Osteochondral transplantation; Surgical treatment

Mesh:

Year:  2014        PMID: 25326766     DOI: 10.1007/s00167-014-3389-3

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  37 in total

1.  Transchondral fractures (osteochondritis dissecans) of the talus.

Authors:  A L BERNDT; M HARTY
Journal:  J Bone Joint Surg Am       Date:  1959-09       Impact factor: 5.284

2.  Mosaicplasty with autogenous talar autograft for osteochondral lesions of the talus after failed primary arthroscopic management: a prospective study with a 4-year follow-up.

Authors:  Peter Cornelius Kreuz; Matthias Steinwachs; Christoph Erggelet; Andreas Lahm; Philipp Henle; Philipp Niemeyer
Journal:  Am J Sports Med       Date:  2005-09-12       Impact factor: 6.202

Review 3.  Mosaicplasty for the treatment of osteochondral defects of the ankle joint.

Authors:  R W Mendicino; A R Catanzariti; R Hallivis
Journal:  Clin Podiatr Med Surg       Date:  2001-07       Impact factor: 1.231

4.  Chondrocyte death associated with human femoral osteochondral harvest as performed for mosaicplasty.

Authors:  J S Huntley; P G Bush; J M McBirnie; A H Simpson; A C Hall
Journal:  J Bone Joint Surg Am       Date:  2005-02       Impact factor: 5.284

5.  The morbidity associated with osteochondral harvest from asymptomatic knees for the treatment of osteochondral lesions of the talus.

Authors:  Sudheer Reddy; David I Pedowitz; Selene G Parekh; Brian J Sennett; Enyi Okereke
Journal:  Am J Sports Med       Date:  2006-09-06       Impact factor: 6.202

6.  Treatment of cartilage defects of the talus by autologous osteochondral grafts.

Authors:  E Gautier; D Kolker; R P Jakob
Journal:  J Bone Joint Surg Br       Date:  2002-03

Review 7.  Cartilage transplantation techniques for talar cartilage lesions.

Authors:  Matthew E Mitchell; Eric Giza; Martin R Sullivan
Journal:  J Am Acad Orthop Surg       Date:  2009-07       Impact factor: 3.020

8.  Oblique medial malleolar osteotomy for the management of talar dome lesions.

Authors:  R W Mendicino; M S Lee; J P Grossman; P J Shromoff
Journal:  J Foot Ankle Surg       Date:  1998 Nov-Dec       Impact factor: 1.286

9.  Donor-site morbidity after osteochondral autograft transfer procedures.

Authors:  Robert F LaPrade; Jesse C Botker
Journal:  Arthroscopy       Date:  2004-09       Impact factor: 4.772

10.  Magnetic resonance imaging features of osteochondral lesions of the talus.

Authors:  Walter C Hembree; Jocelyn R Wittstein; Emily N Vinson; Robin M Queen; Connor R Larose; Kush Singh; Mark E Easley
Journal:  Foot Ankle Int       Date:  2012-07       Impact factor: 2.827

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  12 in total

1.  Good clinical and functional outcomes at mid-term following autologous osteochondral transplantation for osteochondral lesions of the talus.

Authors:  Yoshiharu Shimozono; Eoghan T Hurley; Charles L Myerson; John G Kennedy
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-03-23       Impact factor: 4.342

2.  Treatment of talus osteochondral defects in chronic lateral unstable ankles: small-sized lateral chondral lesions had good clinical outcomes.

Authors:  Hong Li; Yinghui Hua; Hongyun Li; Shengkun Li; Kui Ma; Shiyi Chen
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-06-02       Impact factor: 4.342

3.  Platelet-Rich Plasma and Hyaluronic Acid Are Not Synergistic When Used as Biological Adjuncts with Autologous Osteochondral Transplantation.

Authors:  Niall A Smyth; Keir A Ross; Amgad M Haleem; Charles P Hannon; Christopher D Murawski; Huong T Do; John G Kennedy
Journal:  Cartilage       Date:  2017-02-08       Impact factor: 4.634

4.  Results of the osteochondral autologous transplantation for treatment of osteochondral lesions of the talus with harvesting from the ipsilateral talar articular facets.

Authors:  Dong Dong Wan; Heng Huang; Mao Zhong Hu; Quan Yu Dong
Journal:  Int Orthop       Date:  2022-03-25       Impact factor: 3.479

5.  Management of Hepple Stage V Osteochondral Lesion of the Talus with a Platelet-Rich Plasma Scaffold.

Authors:  Wenqi Gu; Tanzhu Li; Zhongmin Shi; Guohua Mei; Jianfeng Xue; Jian Zou; Xiaokang Wang; Haotong Zhang; Hongwei Xu
Journal:  Biomed Res Int       Date:  2017-03-16       Impact factor: 3.411

Review 6.  No superior surgical treatment for secondary osteochondral defects of the talus.

Authors:  Kaj T A Lambers; Jari Dahmen; Mikel L Reilingh; Christiaan J A van Bergen; Sjoerd A S Stufkens; Gino M M J Kerkhoffs
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-07-07       Impact factor: 4.342

7.  Early postoperative compilations of bone filling in curettage defects.

Authors:  Clark J Chen; Earl W Brien
Journal:  J Orthop Surg Res       Date:  2019-08-16       Impact factor: 2.359

8.  Finite Element Analysis of the Effect of Talar Osteochondral Defects of Different Depths on Ankle Joint Stability.

Authors:  Jia Li; Yu Wei; Min Wei
Journal:  Med Sci Monit       Date:  2020-08-21

9.  Large Osteochondral Lesions of the Talus Treated With Autologous Bone Graft and Periosteum Transfer.

Authors:  Dimitrios Nikolopoulos; Neoptolemos Sergides; George Safos; Konstantinos Moustakas; Petros Safos; Andreas Moutsios-Rentzos
Journal:  Foot Ankle Orthop       Date:  2019-09-11

10.  A comparison between arthroscopic and open surgery for treatment outcomes of chronic lateral ankle instability accompanied by osteochondral lesions of the talus.

Authors:  Can Xu; Mingqing Li; Chenggong Wang; Hua Liu
Journal:  J Orthop Surg Res       Date:  2020-03-20       Impact factor: 2.359

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