Vita Birzniece1, Chong-Hui Khaw2, Anne E Nelson2, Udo Meinhardt3, Ken K Y Ho4. 1. Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia. 2. Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia. 3. Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia. 4. Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia Garvan Institute of Medical Research and Department of EndocrinologySt Vincent's Hospital, Sydney, New South Wales, AustraliaThe University of NSWSydney, New South Wales, AustraliaSchool of MedicineUniversity of Western Sydney, Sydney, New South Wales, AustraliaCentre for Pediatric EndocrinologyZurich, SwitzerlandCentres for Health ResearchPrincess Alexandra Hospital, Brisbane, Queensland, Australia k.ho@uq.edu.au.
Abstract
OBJECTIVE: To compare estimates by bioimpedance spectroscopy analysis (BIS) of extracellular water (ECW), fat mass (FM), and fat-free mass (FFM) against standard techniques of bromide dilution and dual energy X-ray absorptiometry (DXA) during intervention that causes significant changes in water compartments and body composition. METHODS: Body composition analysis using BIS, bromide dilution, and DXA was performed in 71 healthy recreational athletes (43 men, 28 women; aged 18-40 years; BMI 24 ± 0.4 kg/m(2)) who participated in a double-blinded, randomized, placebo-controlled study of GH and testosterone treatment. The comparison of BIS with bromide dilution and DXA was analyzed using linear regression and the Bland-Altman method. RESULTS: At baseline, there was a significant correlation between BIS and bromide dilution-derived estimates for ECW, and DXA for FM and FFM (P<0.001). ECW by BIS was 3.5 ± 8.1% lower compared with bromide dilution, while FM was 22.4 ± 26.8% lower and FFM 13.7 ± 7.5% higher compared with DXA (P<0.01). During treatment, the change in ECW was similar between BIS and bromide dilution, whereas BIS gave a significantly greater reduction in FM (19.4 ± 44.8%) and a greater increase in FFM (5.6 ± 3.0%) compared with DXA (P<0.01). Significant differences in body composition estimates between the BIS and DXA were observed only in men, particularly during the treatment that caused greatest change in water compartments and body composition. CONCLUSION: In healthy adults, bioimpedance spectroscopy is an acceptable tool for measuring ECW; however, BIS overestimates FFM and substantially underestimates FM compared with DXA.
RCT Entities:
OBJECTIVE: To compare estimates by bioimpedance spectroscopy analysis (BIS) of extracellular water (ECW), fat mass (FM), and fat-free mass (FFM) against standard techniques of bromide dilution and dual energy X-ray absorptiometry (DXA) during intervention that causes significant changes in water compartments and body composition. METHODS: Body composition analysis using BIS, bromide dilution, and DXA was performed in 71 healthy recreational athletes (43 men, 28 women; aged 18-40 years; BMI 24 ± 0.4 kg/m(2)) who participated in a double-blinded, randomized, placebo-controlled study of GH and testosterone treatment. The comparison of BIS with bromide dilution and DXA was analyzed using linear regression and the Bland-Altman method. RESULTS: At baseline, there was a significant correlation between BIS and bromide dilution-derived estimates for ECW, and DXA for FM and FFM (P<0.001). ECW by BIS was 3.5 ± 8.1% lower compared with bromide dilution, while FM was 22.4 ± 26.8% lower and FFM 13.7 ± 7.5% higher compared with DXA (P<0.01). During treatment, the change in ECW was similar between BIS and bromide dilution, whereas BIS gave a significantly greater reduction in FM (19.4 ± 44.8%) and a greater increase in FFM (5.6 ± 3.0%) compared with DXA (P<0.01). Significant differences in body composition estimates between the BIS and DXA were observed only in men, particularly during the treatment that caused greatest change in water compartments and body composition. CONCLUSION: In healthy adults, bioimpedance spectroscopy is an acceptable tool for measuring ECW; however, BIS overestimates FFM and substantially underestimates FM compared with DXA.
Authors: Eline Vermeiren; Marijke Ysebaert; Kim Van Hoorenbeeck; Luc Bruyndonckx; Kristof Van Dessel; Maria Van Helvoirt; Ann De Guchtenaere; Benedicte De Winter; Stijn Verhulst; Annelies Van Eyck Journal: Eur J Clin Nutr Date: 2020-09-11 Impact factor: 4.016
Authors: Maria-Eleni Roumelioti; Robert H Glew; Zeid J Khitan; Helbert Rondon-Berrios; Christos P Argyropoulos; Deepak Malhotra; Dominic S Raj; Emmanuel I Agaba; Mark Rohrscheib; Glen H Murata; Joseph I Shapiro; Antonios H Tzamaloukas Journal: World J Nephrol Date: 2018-01-06
Authors: Teresa Lam; Birinder Cheema; Amy Hayden; Stephen R Lord; Howard Gurney; Shivanjini Gounden; Navneeta Reddy; Haleh Shahidipour; Scott Read; Glenn Stone; Mark McLean; Vita Birzniece Journal: Sports Med Open Date: 2020-12-14
Authors: Cody T Haun; Christopher G Vann; Christopher B Mobley; Paul A Roberson; Shelby C Osburn; Hudson M Holmes; Petey M Mumford; Matthew A Romero; Kaelin C Young; Jordan R Moon; L Bruce Gladden; Robert D Arnold; Michael A Israetel; Annie N Kirby; Michael D Roberts Journal: Front Nutr Date: 2018-09-11