Literature DB >> 25325979

Analysis of the heavy-chain modification and TSG-6 activity in pathological hyaluronan matrices.

Mark E Lauer1, Jacqueline Loftis, Carol de la Motte, Vincent C Hascall.   

Abstract

During inflammation and developmental processes, heavy chains (HCs) from inter-α-inhibitor (IαI) are covalently transferred to hyaluronan (HA) via the enzyme tumor-necrosis-factor-stimulated-gene 6 (TSG-6) to form a HC-HA complex. In this manuscript, we describe a gel-based assay to detect HC-HA and TSG-6 activity in tissues.

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Year:  2015        PMID： 25325979      PMCID： PMC4397960          DOI： 10.1007/978-1-4939-1714-3_42

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  4 in total

1.  TSG-6 activity as a novel biomarker of progression in knee osteoarthritis.

Authors:  H-G Wisniewski; E Colón; V Liublinska; R J Karia; T V Stabler; M Attur; S B Abramson; P A Band; V B Kraus
Journal:  Osteoarthritis Cartilage       Date:  2013-12-12       Impact factor: 6.576

2.  TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthma.

Authors:  Shadi Swaidani; Georgiana Cheng; Mark E Lauer; Manisha Sharma; Katalin Mikecz; Vincent C Hascall; Mark A Aronica
Journal:  J Biol Chem       Date:  2012-11-01       Impact factor: 5.157

Review 3.  TSG-6: a pluripotent inflammatory mediator?

Authors:  C M Milner; V A Higman; A J Day
Journal:  Biochem Soc Trans       Date:  2006-06       Impact factor: 5.407

Review 4.  The molecular basis of inter-alpha-inhibitor heavy chain transfer on to hyaluronan.

Authors:  C M Milner; W Tongsoongnoen; M S Rugg; A J Day
Journal:  Biochem Soc Trans       Date:  2007-08       Impact factor: 5.407
  4 in total
  8 in total

1.  Pathological Hyaluronan Matrices in Cystic Fibrosis Airways and Secretions.

Authors:  Brittany Matuska; Suzy Comhair; Carol Farver; James Chmiel; Ronald J Midura; Tracey Bonfield; Mark E Lauer
Journal:  Am J Respir Cell Mol Biol       Date:  2016-10       Impact factor: 6.914

2.  Cutaneous Wounds in Mice Lacking TSG-6 Exhibit Delayed Closure and an Abnormal Inflammatory Response.

Authors:  Sajina Shakya; Judith A Mack; Minou Alipour; Edward V Maytin
Journal:  J Invest Dermatol       Date:  2020-05-15       Impact factor: 8.551

3.  Hyaluronan and Its Heavy Chain Modification in Asthma Severity and Experimental Asthma Exacerbation.

Authors:  Mark E Lauer; Alana K Majors; Suzy Comhair; Lisa M Ruple; Brittany Matuska; Ahila Subramanian; Carol Farver; Ryszard Dworski; Deepa Grandon; Dan Laskowski; Raed A Dweik; Serpil C Erzurum; Vincent C Hascall; Mark A Aronica
Journal:  J Biol Chem       Date:  2015-07-24       Impact factor: 5.157

Review 4.  Defining the versican interactome in lung health and disease.

Authors:  Fengying Tang; Jourdan E Brune; Mary Y Chang; Stephen R Reeves; William A Altemeier; Charles W Frevert
Journal:  Am J Physiol Cell Physiol       Date:  2022-06-01       Impact factor: 5.282

5.  Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury.

Authors:  Kevin Ni; Amar Gill; Victor Tseng; Andrew M Mikosz; Kengo Koike; Erica L Beatman; Cassie Y Xu; Danting Cao; Fabienne Gally; Kara J Mould; Karina A Serban; Kelly S Schweitzer; Keith L March; William J Janssen; Eva Nozik-Grayck; Stavros Garantziotis; Irina Petrache
Journal:  Respir Res       Date:  2018-05-31

6.  Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension.

Authors:  Victor Tseng; Kevin Ni; Ayed Allawzi; Clare Prohaska; Laura Hernandez-Lagunas; Hanan Elajaili; Valbona Cali; Ronald Midura; Vincent Hascall; Barbara Triggs-Raine; Irina Petrache; C Michael Hart; Eva Nozik-Grayck
Journal:  Sci Rep       Date:  2020-01-14       Impact factor: 4.379

7.  Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury.

Authors:  Vivien J Coulson-Thomas; Mark E Lauer; Sara Soleman; Chao Zhao; Vincent C Hascall; Anthony J Day; James W Fawcett
Journal:  J Biol Chem       Date:  2016-07-19       Impact factor: 5.157

8.  COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction.

Authors:  Kimberly A Queisser; Rebecca A Mellema; Elizabeth A Middleton; Irina Portier; Bhanu Kanth Manne; Frederik Denorme; Ellen J Beswick; Matthew T Rondina; Robert A Campbell; Aaron C Petrey
Journal:  JCI Insight       Date:  2021-09-08
  8 in total

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