Literature DB >> 25325177

Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233.

Mangaladoss Fredimoses1, Xuefeng Zhou, Wen Ai, Xinpeng Tian, Bin Yang, Xiuping Lin, Jia-Yun Xian, Yonghong Liu.   

Abstract

A new methyl 2-(4-((2-hydroxy-3-methylbut-3-en-1-yl)oxy)phenyl) acetate 1, together with five known compounds 2-6, was isolated from the culture of the deep sea-derived fungus Aspergillus westerdijkiae SCSIO 05233. The new structure was determined by NMR ((1)H and (13)C NMR, HSQC, HMBC and MS) and optical rotation analysis. Compound 5 displayed weak inhibitory activities towards K562 and promyelocytic HL-60 with IC50 values of 25.8 and 44.9 μM, and compound 6 showed strong antifouling activity with EC50 value 8.81 μg/mL.

Entities:  

Keywords:  Aspergillus westerdijkiae; antifouling; cytotoxicity; deep sea

Mesh：

Substances：

Year:  2014        PMID： 25325177     DOI： 10.1080/14786419.2014.968154

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  10 in total

Review 1.  Recent updates on the bioactive compounds of the marine-derived genus Aspergillus.

Authors:  Raha Orfali; Mahmoud A Aboseada; Nada M Abdel-Wahab; Hossam M Hassan; Shagufta Perveen; Fuad Ameen; Eman Alturki; Usama Ramadan Abdelmohsen
Journal:  RSC Adv       Date:  2021-05-11       Impact factor: 4.036

Review 2.  Marine Fungi: A Source of Potential Anticancer Compounds.

Authors:  Sunil K Deshmukh; Ved Prakash; Nihar Ranjan
Journal:  Front Microbiol       Date:  2018-01-05       Impact factor: 5.640

Review 3.  Mini-Review: Antifouling Natural Products from Marine Microorganisms and Their Synthetic Analogs.

Authors:  Kai-Ling Wang; Ze-Hong Wu; Yu Wang; Chang-Yun Wang; Ying Xu
Journal:  Mar Drugs       Date:  2017-08-28       Impact factor: 5.118

Review 4.  Anti-Larval and Anti-Algal Natural Products from Marine Microorganisms as Sources of Anti-Biofilm Agents.

Authors:  Kai-Ling Wang; Zheng-Rong Dou; Gao-Fen Gong; Hai-Feng Li; Bei Jiang; Ying Xu
Journal:  Mar Drugs       Date:  2022-01-21       Impact factor: 5.118

5.  Cyclic Tetrapeptides with Synergistic Antifungal Activity from the Fungus Aspergillus westerdijkiae Using LC-MS/MS-Based Molecular Networking.

Authors:  Junjie Han; Hanying Wang; Rui Zhang; Huanqin Dai; Baosong Chen; Tao Wang; Jingzu Sun; Wenzhao Wang; Fuhang Song; Erwei Li; Zhitang Lyu; Hongwei Liu
Journal:  Antibiotics (Basel)       Date:  2022-01-27

Review 6.  A Brief Review of Bioactive Metabolites Derived from Deep-Sea Fungi.

Authors:  Yan-Ting Wang; Ya-Rong Xue; Chang-Hong Liu
Journal:  Mar Drugs       Date:  2015-07-23       Impact factor: 5.118

7.  Sequencing and functional annotation of the whole genome of the filamentous fungus Aspergillus westerdijkiae.

Authors:  Xiaolong Han; Alolika Chakrabortti; Jindong Zhu; Zhao-Xun Liang; Jinming Li
Journal:  BMC Genomics       Date:  2016-08-15       Impact factor: 3.969

Review 8.  Novel Natural Products from Extremophilic Fungi.

Authors:  Xuan Zhang; Shou-Jie Li; Jin-Jie Li; Zi-Zhen Liang; Chang-Qi Zhao
Journal:  Mar Drugs       Date:  2018-06-04       Impact factor: 5.118

9.  Phytotoxic Metabolites Isolated from Neufusicoccum batangarum, the Causal Agent of the Scabby Canker of Cactus Pear (Opuntia ficus-indica L.).

Authors:  Marco Masi; Francesco Aloi; Paola Nocera; Santa Olga Cacciola; Giuseppe Surico; Antonio Evidente
Journal:  Toxins (Basel)       Date:  2020-02-18       Impact factor: 4.546

Review 10.  Deep-Sea Fungi Could Be the New Arsenal for Bioactive Molecules.

Authors:  Muhammad Zain Ul Arifeen; Yu-Nan Ma; Ya-Rong Xue; Chang-Hong Liu
Journal:  Mar Drugs       Date:  2019-12-20       Impact factor: 5.118
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.