Literature DB >> 25323926

Dynamic bias and its implications for GPCR drug discovery.

Martin C Michel1, Roland Seifert2, Richard A Bond3.   

Abstract

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Year:  2014        PMID： 25323926     DOI： 10.1038/nrd3954-c3

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  5 in total

1.  Longitudinal trends and subgroup analysis in publication patterns for preclinical data of newly approved drugs.

Authors:  Ursula Köster; Ingo Nolte; Martin C Michel
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2015-11-26       Impact factor: 3.000

2.  GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

Authors:  Alexander Heifetz; Gebhard F X Schertler; Roland Seifert; Christopher G Tate; Patrick M Sexton; Vsevolod V Gurevich; Daniel Fourmy; Vadim Cherezov; Fiona H Marshall; R Ian Storer; Isabel Moraes; Irina G Tikhonova; Christofer S Tautermann; Peter Hunt; Tom Ceska; Simon Hodgson; Mike J Bodkin; Shweta Singh; Richard J Law; Philip C Biggin
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2015-03-14       Impact factor: 3.000

3.  G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.

Authors:  Lauriane Onfroy; Ségolène Galandrin; Stéphanie M Pontier; Marie-Hélène Seguelas; Du N'Guyen; Jean-Michel Sénard; Céline Galés
Journal:  Sci Rep       Date:  2017-08-11       Impact factor: 4.379

4.  A Systematic Review of Inverse Agonism at Adrenoceptor Subtypes.

Authors:  Martin C Michel; Martina B Michel-Reher; Peter Hein
Journal:  Cells       Date:  2020-08-19       Impact factor: 6.600

5.  Comprehensive Signaling Profiles Reveal Unsuspected Functional Selectivity of δ-Opioid Receptor Agonists and Allow the Identification of Ligands with the Greatest Potential for Inducing Cyclase Superactivation.

Authors:  Ahmed Mansour; Karim Nagi; Paul Dallaire; Viktoriya Lukasheva; Christian Le Gouill; Michel Bouvier; Graciela Pineyro
Journal:  ACS Pharmacol Transl Sci       Date:  2021-09-09
  5 in total

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