BACKGROUND: Both patient survival and the proportion of patients diagnosed with thin cutaneous malignant melanoma (CMM) have been steadily rising in Sweden as in most Western countries, although the rate of improvement in survival appears to have declined in Sweden at the end of the last millennium. OBJECTIVES: To analyse the most recent trends in the distribution of tumour thickness (T category) as well as CMM-specific survival in Swedish patients diagnosed during 1997-2011. METHODS: This nationwide population-based study included 30,590 patients registered in the Swedish Melanoma Register (SMR) and diagnosed with a first primary invasive CMM during 1997-2011. The patients were followed through 2012 in the national Cause of Death Register. RESULTS: Logistic and Cox regression analyses adjusting for age at diagnosis, tumour site and healthcare region were carried out. The odds ratio for being diagnosed with thicker tumours was significantly reduced (P < 0·001) and the CMM-specific survival significantly improved in men diagnosed during 2007-2011 compared with men diagnosed during 1997-2001 (hazard ratio = 0·81; 95% confidence interval 0·72-0·91; P < 0·001), while the corresponding differences for women were not significant. Women were diagnosed with significantly thicker tumours during 2002-2006 and a tendency towards decreased survival was observed compared with those diagnosed earlier (during 1997-2001) and later (during 2007-2011). CONCLUSIONS: In Sweden, the CMMs of men are detected earlier over time and this seems to be followed by an improved CMM-specific survival for men. Women are still diagnosed with considerably thinner tumours and they experience a better survival than men.
BACKGROUND: Both patient survival and the proportion of patients diagnosed with thin cutaneous malignant melanoma (CMM) have been steadily rising in Sweden as in most Western countries, although the rate of improvement in survival appears to have declined in Sweden at the end of the last millennium. OBJECTIVES: To analyse the most recent trends in the distribution of tumour thickness (T category) as well as CMM-specific survival in Swedish patients diagnosed during 1997-2011. METHODS: This nationwide population-based study included 30,590 patients registered in the Swedish Melanoma Register (SMR) and diagnosed with a first primary invasive CMM during 1997-2011. The patients were followed through 2012 in the national Cause of Death Register. RESULTS: Logistic and Cox regression analyses adjusting for age at diagnosis, tumour site and healthcare region were carried out. The odds ratio for being diagnosed with thicker tumours was significantly reduced (P < 0·001) and the CMM-specific survival significantly improved in men diagnosed during 2007-2011 compared with men diagnosed during 1997-2001 (hazard ratio = 0·81; 95% confidence interval 0·72-0·91; P < 0·001), while the corresponding differences for women were not significant. Women were diagnosed with significantly thicker tumours during 2002-2006 and a tendency towards decreased survival was observed compared with those diagnosed earlier (during 1997-2001) and later (during 2007-2011). CONCLUSIONS: In Sweden, the CMMs of men are detected earlier over time and this seems to be followed by an improved CMM-specific survival for men. Women are still diagnosed with considerably thinner tumours and they experience a better survival than men.
Authors: Trude Eid Robsahm; Per Helsing; Yngvar Nilssen; Linda Vos; Syed Mohammad H Rizvi; Lars A Akslen; Marit B Veierød Journal: Clin Epidemiol Date: 2018-05-09 Impact factor: 4.790
Authors: Veronica Di Carlo; Charles A Stiller; Nora Eisemann; Andrea Bordoni; Melissa Matz; Maria P Curado; Laetitia Daubisse-Marliac; Mikhail Valkov; Jean-Luc Bulliard; David Morrison; Chris Johnson; Fabio Girardi; Rafael Marcos-Gragera; Mario Šekerija; Siri Larønningen; Eunice Sirri; Michel P Coleman; Claudia Allemani Journal: Br J Dermatol Date: 2022-07-28 Impact factor: 11.113
Authors: Alberto Julius Alves Wainstein; João Pedreira Duprat Neto; Mauro Yoshiaki Enokihara; Eduard René Brechtbühl; Felice Riccardi; Gilles Landman; Andreia Cristina de Melo; Vinicius de Lima Vazquez; Rodrigo Ramella Munhoz; Ivan Dunshee De Abranches Oliveira Santos Filho; Eduardo Bertolli; Ana Paula Drummond-Lage; Bianca Costa Soares de Sá; Luciane Botelho; Jose Higino Steck; Francisco Aparecido Belfort; Marcus Maia; Renato Marchiori Bakos; Elimar Elias Gomes; Rafael Schmerling; Flavio Cavarsan Journal: JCO Glob Oncol Date: 2020-04