Literature DB >> 25323489

[Insulin or surgery? : the perspective of a diabetologist].

M Blüher1.   

Abstract

Obesity significantly increases the risk of developing type 2 diabetes by a factor of up to 9. Medical treatment of type 2 diabetes with lifestyle and pharmacological interventions frequently fails to prevent the progress of the disease and the manifestation of diabetes complications. In recent years bariatric metabolic surgery has emerged as an effective treatment for patients with obesity and type 2 diabetes. Compared to medical treatment alone, metabolic surgery has been shown to be more effective in reducing mortality, improving hyperglycemia, hypertension and dyslipidemia in randomized clinical trials among patients with obesity and type 2 diabetes. However, surgery also has the risk for acute perioperative complications, long-term micronutrient deficiencies and psychological problems. Weighing these risks against the benefits of significant weight loss and improved glycemic control, metabolic surgery seems to be a promising treatment option for obesity-associated type 2 diabetes. However, current guidelines and treatment algorithms for the treatment of type 2 diabetes either ignore or underestimate the potential of metabolic surgery. In my opinion, metabolic surgery should be considered earlier in the treatment of type 2 diabetes and obesity and no longer be considered as the last therapeutic option for patients with obesity-associated type 2 diabetes.

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Year:  2014        PMID: 25323489     DOI: 10.1007/s00104-014-2795-x

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  33 in total

1.  Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001.

Authors:  Ali H Mokdad; Earl S Ford; Barbara A Bowman; William H Dietz; Frank Vinicor; Virginia S Bales; James S Marks
Journal:  JAMA       Date:  2003-01-01       Impact factor: 56.272

2.  Metabolically healthy but obese women: effect of an energy-restricted diet.

Authors:  A D Karelis; V Messier; M Brochu; R Rabasa-Lhoret
Journal:  Diabetologia       Date:  2008-05-27       Impact factor: 10.122

3.  Bariatric surgery versus intensive medical therapy for diabetes--3-year outcomes.

Authors:  Philip R Schauer; Deepak L Bhatt; John P Kirwan; Kathy Wolski; Stacy A Brethauer; Sankar D Navaneethan; Ali Aminian; Claire E Pothier; Esther S H Kim; Steven E Nissen; Sangeeta R Kashyap
Journal:  N Engl J Med       Date:  2014-03-31       Impact factor: 91.245

4.  Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.

Authors:  Rena R Wing; Paula Bolin; Frederick L Brancati; George A Bray; Jeanne M Clark; Mace Coday; Richard S Crow; Jeffrey M Curtis; Caitlin M Egan; Mark A Espeland; Mary Evans; John P Foreyt; Siran Ghazarian; Edward W Gregg; Barbara Harrison; Helen P Hazuda; James O Hill; Edward S Horton; Van S Hubbard; John M Jakicic; Robert W Jeffery; Karen C Johnson; Steven E Kahn; Abbas E Kitabchi; William C Knowler; Cora E Lewis; Barbara J Maschak-Carey; Maria G Montez; Anne Murillo; David M Nathan; Jennifer Patricio; Anne Peters; Xavier Pi-Sunyer; Henry Pownall; David Reboussin; Judith G Regensteiner; Amy D Rickman; Donna H Ryan; Monika Safford; Thomas A Wadden; Lynne E Wagenknecht; Delia S West; David F Williamson; Susan Z Yanovski
Journal:  N Engl J Med       Date:  2013-06-24       Impact factor: 91.245

5.  An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes.

Authors:  Matthias B Schulze; Kurt Hoffmann; Heiner Boeing; Jakob Linseisen; Sabine Rohrmann; Matthias Möhlig; Andreas F H Pfeiffer; Joachim Spranger; Claus Thamer; Hans-Ulrich Häring; Andreas Fritsche; Hans-Georg Joost
Journal:  Diabetes Care       Date:  2007-03       Impact factor: 19.112

6.  Glucose control and vascular complications in veterans with type 2 diabetes.

Authors:  William Duckworth; Carlos Abraira; Thomas Moritz; Domenic Reda; Nicholas Emanuele; Peter D Reaven; Franklin J Zieve; Jennifer Marks; Stephen N Davis; Rodney Hayward; Stuart R Warren; Steven Goldman; Madeline McCarren; Mary Ellen Vitek; William G Henderson; Grant D Huang
Journal:  N Engl J Med       Date:  2008-12-17       Impact factor: 91.245

7.  Effects of intensive glucose lowering in type 2 diabetes.

Authors:  Hertzel C Gerstein; Michael E Miller; Robert P Byington; David C Goff; J Thomas Bigger; John B Buse; William C Cushman; Saul Genuth; Faramarz Ismail-Beigi; Richard H Grimm; Jeffrey L Probstfield; Denise G Simons-Morton; William T Friedewald
Journal:  N Engl J Med       Date:  2008-06-06       Impact factor: 91.245

Review 8.  Are metabolically healthy obese individuals really healthy?

Authors:  Matthias Blüher
Journal:  Eur J Endocrinol       Date:  2014-07-10       Impact factor: 6.664

9.  Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.

Authors: 
Journal:  Lancet       Date:  1998-09-12       Impact factor: 79.321

10.  Bariatric surgery: an IDF statement for obese Type 2 diabetes.

Authors:  J B Dixon; P Zimmet; K G Alberti; F Rubino
Journal:  Diabet Med       Date:  2011-06       Impact factor: 4.359

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  3 in total

1.  [Metabolic surgery].

Authors:  B P Müller-Stich; M W Büchler
Journal:  Chirurg       Date:  2014-11       Impact factor: 0.955

2.  [Pharmacological therapy versus bariatric surgery for patients with obesity and type 2 diabetes].

Authors:  M Blüher
Journal:  Internist (Berl)       Date:  2015-02       Impact factor: 0.743

3.  NEW TECHNIQUE FOR OBESITY SURGERY: INTERNAL GASTRIC PLICATION TECHNIQUE USING INTRAGASTRIC SINGLE-PORT (IGS-IGP) IN EXPERIMENTAL MODEL.

Authors:  Verena Müller; Panagiotis Fikatas; Safak Gül; Maximilian Noesser; Kirs Ten Fuehrer; Igor Sauer; Johann Pratschke; Ricardo Zorron
Journal:  Arq Bras Cir Dig       Date:  2017 Jan-Mar
  3 in total

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