Béatrice Clarivet1, Eric Picot2, Hélène Marchandin3, Vincent Tribout2, Nadia Rachedi2, Eric Schwartzentruber4, Bernard Ledésert5, Olivier Dereure6, Bernard Guillot6, Marie-Christine Picot7. 1. Unité de Recherche Clinique et Epidémiologie, Hôpital La Colombière, Montpellier, France. 2. CDAG/CIDDIST. 3. Département de Bactériologie, Hôpital Arnaud de Villeneuve, Montpellier, France, Université Montpellier 1 UMR 5119 ECOSYM, Montpellier, France. 4. DRASS Languedoc-Roussillon. 5. Observatoire Régional de la Santé du Languedoc Roussillon. 6. Service de Dermatologie Hôpital Saint-Eloi 34295 Montpellier, France, Inserm Unité1058, UFR de Pharmacie 15, Montpellier, France. 7. Unité de Recherche Clinique et Epidémiologie, Hôpital La Colombière, Montpellier, France, Centre d'Investigation Clinique, Inserm Unité 1001.
Abstract
BACKGROUND: An increasing prevalence of sexually transmitted infections (STI) has been noted in France over the past decade. Asymptomatic carriage may be high in patients infected with Chlamydia trachomatis attending free and anonymous screening centres (CDAG) and information, diagnosis and screening centres for STI (CIDDIST). In these centres, systematic C. trachomatis detection is recommended in women ≤25 years and in men ≤30 years. OBJECTIVES: This study aimed at estimating the prevalence of C. trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium in asymptomatic patients younger than 30 years attending a CDAG-CIDDIST. MATERIAL AND METHODS: A free systematic screening for C. trachomatis, N. gonorrhoeae and M. genitalium was offered to asymptomatic subjects under 30 years attending the Montpellier CDAG-CIDDIST from April to August 2009. Pathogens were identified by PCR in first void urine samples. RESULTS: Of the 1381 subjects included (53.8% women and 46.2% men), 105 (42.9% men and 57.1% women) tested positive for C. trachomatis (7.6%, 95% CI [6.3;9.13]); eight (seven men and one woman) tested positive for M. genitalium (0.58% [0.2;1]) of whom two were infected with C. trachomatis ; five (two men and three women) tested positive for N. gonorrhoeae (0.36% [0.1;0.8]) of whom three were infected with C. trachomatis. CONCLUSION: This study confirmed the need for C. trachomatis screening in all patients under 30 years. Our results did not support a systematic screening for N. gonorrhoeae and M. genitalium in urine samples in this kind of facility.
BACKGROUND: An increasing prevalence of sexually transmitted infections (STI) has been noted in France over the past decade. Asymptomatic carriage may be high in patients infected with Chlamydia trachomatis attending free and anonymous screening centres (CDAG) and information, diagnosis and screening centres for STI (CIDDIST). In these centres, systematic C. trachomatis detection is recommended in women ≤25 years and in men ≤30 years. OBJECTIVES: This study aimed at estimating the prevalence of C. trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium in asymptomatic patients younger than 30 years attending a CDAG-CIDDIST. MATERIAL AND METHODS: A free systematic screening for C. trachomatis, N. gonorrhoeae and M. genitalium was offered to asymptomatic subjects under 30 years attending the Montpellier CDAG-CIDDIST from April to August 2009. Pathogens were identified by PCR in first void urine samples. RESULTS: Of the 1381 subjects included (53.8% women and 46.2% men), 105 (42.9% men and 57.1% women) tested positive for C. trachomatis (7.6%, 95% CI [6.3;9.13]); eight (seven men and one woman) tested positive for M. genitalium (0.58% [0.2;1]) of whom two were infected with C. trachomatis ; five (two men and three women) tested positive for N. gonorrhoeae (0.36% [0.1;0.8]) of whom three were infected with C. trachomatis. CONCLUSION: This study confirmed the need for C. trachomatis screening in all patients under 30 years. Our results did not support a systematic screening for N. gonorrhoeae and M. genitalium in urine samples in this kind of facility.
Authors: Arlene C Seña; Jeannette Y Lee; Jane Schwebke; Susan S Philip; Harold C Wiesenfeld; Anne M Rompalo; Robert L Cook; Marcia M Hobbs Journal: Clin Infect Dis Date: 2018-06-18 Impact factor: 9.079
Authors: J F Braam; L van Dommelen; C J M Henquet; J H B van de Bovenkamp; J G Kusters Journal: Eur J Clin Microbiol Infect Dis Date: 2017-03-30 Impact factor: 3.267