| Literature DB >> 25322072 |
Masayoshi Mochizuki1, Hajime Hibino, Yuji Nishiuchi.
Abstract
Tritylation using trityl alcohol (Trt-OH) in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) is a convenient and efficient procedure that can offer S-protection of the Cys located in fully unprotected peptides. The procedure simply requires Trt-OH and HFIP to selectively promote S-tritylation in the presence of peptide nucleophilic functionalities.Entities:
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Year: 2014 PMID： 25322072 DOI： 10.1021/ol502773v
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005