| Literature DB >> 25321843 |
Simona Bonollo1, Amanollah Zarei Ahmady, Chiara Petrucci, Assunta Marrocchi, Ferdinando Pizzo, Luigi Vaccaro.
Abstract
The first catalytic approach to the nucleophilic addition of silyl ketene acetals 2 to epoxides 1 is reported. The defined protocol is metal-free using tetrabutylammonioum fluoride as the catalyst. It works in a very efficient manner under solvent-free conditions (SolFC) allowing γ-lactones 3 to be directly obtained with high regioselectivities and yields.Entities:
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Year: 2014 PMID： 25321843 DOI： 10.1021/ol502855q
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005