Ajit Ninan1, Shannon L Stewart2, Laura A Theall3, Shehan Katuwapitiya4, Chester Kam5. 1. Child and Parent Resource Institute, London, Ontario ; Western University, London, Ontario. 2. Western University, London, Ontario ; Child and Parent Resource Institute, London, Ontario. 3. Child and Parent Resource Institute, London, Ontario. 4. Western University, London, Ontario. 5. University of Macau, Macau, China.
Abstract
OBJECTIVE: Despite limited information related to efficacy in children, psychotropic medications are commonly prescribed as a first-line treatment for a range of psychiatric diagnoses in children in a variety of clinical settings. Usage has increased over the past three decades. Although psychotropic medications are often effective at treating psychiatric symptoms, the risk of adverse effects (AE) in children is unclear. The current research seeks to identify the mental health characteristics of those children at highest risk of experiencing potential AE from psychotropic medications. METHODS: Psychotropic medication monitoring checklists were used to record possible AE for 99 pediatric clients in a tertiary mental health residential treatment centre for the duration of one to eight weeks. Client characteristics, including the number of diagnoses and behavioural variables, were explored for predictive value of potential AE observed. RESULTS: Results showed that the total number of potential AE was positively predicted by the number of DSM-IV categories diagnosed, as well as behavioural symptoms of impulsiveness and uncooperativeness. CONCLUSIONS: The findings of this study indicate that the number of potential AE from psychotropic medications may be predictable based on client characteristics. Predicting this likelihood during initial assessment can be useful in directing and monitoring treatment, as well as preventing serious events related to medication use.
OBJECTIVE: Despite limited information related to efficacy in children, psychotropic medications are commonly prescribed as a first-line treatment for a range of psychiatric diagnoses in children in a variety of clinical settings. Usage has increased over the past three decades. Although psychotropic medications are often effective at treating psychiatric symptoms, the risk of adverse effects (AE) in children is unclear. The current research seeks to identify the mental health characteristics of those children at highest risk of experiencing potential AE from psychotropic medications. METHODS: Psychotropic medication monitoring checklists were used to record possible AE for 99 pediatric clients in a tertiary mental health residential treatment centre for the duration of one to eight weeks. Client characteristics, including the number of diagnoses and behavioural variables, were explored for predictive value of potential AE observed. RESULTS: Results showed that the total number of potential AE was positively predicted by the number of DSM-IV categories diagnosed, as well as behavioural symptoms of impulsiveness and uncooperativeness. CONCLUSIONS: The findings of this study indicate that the number of potential AE from psychotropic medications may be predictable based on client characteristics. Predicting this likelihood during initial assessment can be useful in directing and monitoring treatment, as well as preventing serious events related to medication use.
Entities:
Keywords:
adverse effects; children; psychotropic medication monitoring checklist; residential care
Authors: Ajit Ninan; Shannon L Stewart; Laura Theall; Gillian King; Ross Evans; Philip Baiden; Al Brown Journal: J Can Acad Child Adolesc Psychiatry Date: 2014-02
Authors: Linmarie Sikich; Robert M Hamer; Robert A Bashford; Brian B Sheitman; Jeffrey A Lieberman Journal: Neuropsychopharmacology Date: 2004-01 Impact factor: 7.853