Literature DB >> 25320547

Intramedullary spinal cord metastasis from pancreatic neuroendocrine tumor.

Jung Ho Kim1, Chang Lim Hyun1, Sang Hoon Han1.   

Abstract

Intramedullary spinal cord metastasis (ISCM) is very rare and its optimal treatment remains controversial. Pancreatic neuroendocrine tumor (pNET) is a rare tumor that usually presents with hepatic metastasis. Hepatic failure due to tumor progression is the major cause of death in cases of pNET. To date, no report has described a case of ISCM from pNET. Although spinal cord metastasis of a solid tumor is uncommon, it is a critical condition that can cause a potentially irreversible loss of neurologic function. Here, we report the case of a 45-year-old man who presented with leg weakness and voiding difficulty, and was found to have ISCM from pNET. Surgical treatment prevented further neurological deterioration. This is the first case report of ISCM from pNET.

Entities:  

Keywords:  Intramedullary; Metastasis; Neuroendocrine tumor; Pancreas; Spinal cord neoplasm

Mesh:

Substances:

Year:  2014        PMID: 25320547      PMCID: PMC4194593          DOI: 10.3748/wjg.v20.i38.14063

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  16 in total

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Review 5.  Neuroendocrine tumors of the pancreas: what's new. Highlights from the "2010 ASCO Gastrointestinal Cancers Symposium". Orlando, FL, USA. January 22-24, 2010.

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