Literature DB >> 25320260

Delayed onset pulmonary glue emboli in a ventilated patient: a rare complication following endoscopic cyanoacrylate injection for gastric variceal haemorrhage.

Joyce Ruo Yi Chew1, Anu Balan2, William Griffiths3, Jurgen Herre1.   

Abstract

Cyanoacrylate injection is a recognised endoscopic treatment option for variceal haemorrhage. We describe a 34-year old man with hepatitis B cirrhosis who presented to the hospital with upper gastrointestinal haemorrhage from gastric and oesophageal varices. Haemostasis was achieved via cyanoacrylate injection sclerotherapy and banding. Ten days later, the patient developed acute hypoxia and fever. His chest radiograph showed wide-spread pulmonary shadowing. A non-contrast CT scan confirmed multiple emboli of injected glue material from the varix with parenchymal changes either suggesting acute lung injury or pulmonary oedema. He gradually recovered with supportive treatment and was discharged home. On follow-up, he remained asymptomatic from a chest perspective. This case report discusses the rare complication of pulmonary embolisation of cyanoacrylate glue from variceal injection sites and the diagnostic dilemmas involved. Emphasis is placed on the importance of maintaining high index of clinical suspicion when assessing patients with possible procedure related complications. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25320260      PMCID: PMC4202042          DOI: 10.1136/bcr-2014-206461

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  32 in total

1.  Multiple pulmonary glue emboli following gastric variceal obliteration.

Authors:  A A Palejwala; H L Smart; M Hughes
Journal:  Endoscopy       Date:  2000-01       Impact factor: 10.093

2.  Septic complications after injection of N-butyl-2-cyanoacrylate: report of two cases and review.

Authors:  Peter Wahl; Franz Lammer; Dieter Conen; Rolf Schlumpf; Andreas Bock
Journal:  Gastrointest Endosc       Date:  2004-06       Impact factor: 9.427

3.  Splenic infarction complicated by splenic artery occlusion after N-butyl-2-cyanoacrylate injection for gastric varices: case report.

Authors:  Li-Kuang Yu; Chao-Wei Hsu; Jeng-Hwei Tseng; Nai-Jen Liu; I-Shyan Sheen
Journal:  Gastrointest Endosc       Date:  2005-02       Impact factor: 9.427

4.  Clinical challenges and images in GI. Pulmonary embolization of histoacryl "glue" causing hypoxia and cardiovascular instability.

Authors:  Philip A Berry; Timothy J Cross; David W Orr
Journal:  Gastroenterology       Date:  2007-11       Impact factor: 22.682

5.  A case of portal and splenic vein thrombosis after Histoacryl injection therapy in gastric varices.

Authors:  C S Shim; Y D Cho; J O Kim; H K Bong; Y S Kim; J S Lee; M S Lee; S G Hwang
Journal:  Endoscopy       Date:  1996-06       Impact factor: 10.093

6.  N-2-butyl-cyanoacrylate for bleeding gastric varices: a United States pilot study and cost analysis.

Authors:  Bruce D Greenwald; Stephen H Caldwell; Elizabeth E Hespenheide; James T Patrie; Jeffrey Williams; Kenneth F Binmoeller; Lysa Woodall; Oleh Haluszka
Journal:  Am J Gastroenterol       Date:  2003-09       Impact factor: 10.864

7.  Cost-effectiveness of N-butyl-2-cyanoacrylate (histoacryl) glue injections versus transjugular intrahepatic portosystemic shunt in the management of acute gastric variceal bleeding.

Authors:  S Mahadeva; M C Bellamy; D Kessel; M H Davies; C E Millson
Journal:  Am J Gastroenterol       Date:  2003-12       Impact factor: 10.864

8.  N-butyl-2-cyanoacrylate and lipoidol pulmonary embolism (glue embolism).

Authors:  Asim Javed; Amjad Salamat
Journal:  J Ayub Med Coll Abbottabad       Date:  2008 Apr-Jun

9.  The use of thrombin injections in the management of bleeding gastric varices: a single-center experience.

Authors:  Jayapal Ramesh; Jimmy K Limdi; Vikram Sharma; Alistair J Makin
Journal:  Gastrointest Endosc       Date:  2008-06-04       Impact factor: 9.427

10.  Pulmonary embolization of 2-octyl cyanoacrylate after endoscopic injection therapy for gastric variceal bleeding.

Authors:  Otis B Rickman; James P Utz; Gregory L Aughenbaugh; Christopher J Gostout
Journal:  Mayo Clin Proc       Date:  2004-11       Impact factor: 7.616

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  5 in total

1.  Pulmonary Glue Embolism: An unusual complication following endoscopic sclerotherapy for gastric varices.

Authors:  Philips G Michael; Georgios Antoniades; Anca Staicu; Shahid Seedat
Journal:  Sultan Qaboos Univ Med J       Date:  2018-09-09

Review 2.  Pitfalls in histoacryl glue injection therapy for oesophageal, gastric and ectopic varices: A review.

Authors:  Lulia Al-Hillawi; Terence Wong; Giovanni Tritto; Philip A Berry
Journal:  World J Gastrointest Surg       Date:  2016-11-27

3.  Duodenal variceal bleed: an unusual cause of upper gastrointestinal bleed and a difficult diagnosis to make.

Authors:  Shradha Bhagani; Conchubhair Winters; Sulleman Moreea
Journal:  BMJ Case Rep       Date:  2017-02-27

4.  Thromboembolic Events Secondary to Endoscopic Cyanoacrylate Injection: Can We Foresee Any Red Flags?

Authors:  Yujen Tseng; Lili Ma; Tiancheng Luo; Xiaoqing Zeng; Yichao Wei; Ling Li; Pengju Xu; Shiyao Chen
Journal:  Can J Gastroenterol Hepatol       Date:  2018-04-03

5.  A case report of bleeding from a duodenal varix: Rare cause of upper gastrointestinal bleeding.

Authors:  Vincent Khor; Yuen Soon; Lwin Aung
Journal:  Int J Surg Case Rep       Date:  2018-06-28
  5 in total

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