Lucia Cugusi1, Paolo Solla2, Francesca Zedda3, Martina Loi3, Roberto Serpe4, Antonino Cannas5, Francesco Marrosu5, Giuseppe Mercuro1. 1. Department of Medical Sciences "M. Aresu", University of Cagliari, Cagliari, Italy Adapted Physical Activity Master Degree Course, University of Cagliari, Cagliari, Italy. 2. Movement Disorders Center, Institute of Neurology, University of Cagliari, Cagliari, Italy Adapted Physical Activity Master Degree Course, University of Cagliari, Cagliari, Italy. 3. Adapted Physical Activity Master Degree Course, University of Cagliari, Cagliari, Italy. 4. Department of Medical Sciences "M. Aresu", University of Cagliari, Cagliari, Italy. 5. Movement Disorders Center, Institute of Neurology, University of Cagliari, Cagliari, Italy.
Abstract
BACKGROUND: Several studies have clearly shown that strategies of health promotion, such as fitness and general exercise programs, may improve quality of life (QoL), motor and non-motor functions in Parkinson's disease (PD) patients. However, little is known about the effects of specific Adapted Physical Activity (APA) programs on PD patients. OBJECTIVE: To determine the effects of an APA program on motor and non-motor symptoms, functional performances and QoL in PD patients. METHODS: Nine consecutive PD patients (5 men, 4 women, 64.4 ± 6.8 years) able to ambulate independently (Hoehn and Yahr: from stage 1 to 3) and not demented, were enrolled. Patients performed an APA program, 3 sessions/week, for 9 weeks. Exercises focused on balance, walking, strength and functional activities. Functional effects were assessed by Six Minute Walking Test (6MWT), Five Time Sit to Stand Test (FTSST), Berg Balance Scale (BBS), Sit and Reach Test (SRT), and Timed Up and Go test (TUG). Motor impairment and disability were assessed using the Unified Parkinson's Disease Rating Scale - part III (UPDRS-III) and the Hoehn and Yahr Scale, respectively. Non-motor symptoms were evaluated by PD Fatigue Scale (PFS), Beck Depression Inventory II (BDI-II) and PD Quality of life scale, 8 items (PDQ-8). RESULTS: A significant decrease in resting HR (67.55 ± 10.85 vs 70.22 ± 12.34 bpm, p < 0.05) and a significant increase in walked distance (p < 0.0005) were observed. A significant impairment of the muscles strength was noted (FTSST, p < 0.05). BBS showed a significant increase in balance abilities (p < 0.0005) and safety with mobility (TUG, p < 0.005) was enhanced. Finally, a significant improvement in motor and non-motor symptoms was detected: UPDRS-III (p < 0.00005), PFS (p < 0.005), BDI-II (p < 0.05) and PDQ-8 (p < 0.05). CONCLUSIONS: A tailored exercise program in PD patients could be effective as an adjunct to conventional therapy on improving daily activities, motor and non-motor symptoms, with better QoL.
BACKGROUND: Several studies have clearly shown that strategies of health promotion, such as fitness and general exercise programs, may improve quality of life (QoL), motor and non-motor functions in Parkinson's disease (PD) patients. However, little is known about the effects of specific Adapted Physical Activity (APA) programs on PDpatients. OBJECTIVE: To determine the effects of an APA program on motor and non-motor symptoms, functional performances and QoL in PDpatients. METHODS: Nine consecutive PDpatients (5 men, 4 women, 64.4 ± 6.8 years) able to ambulate independently (Hoehn and Yahr: from stage 1 to 3) and not demented, were enrolled. Patients performed an APA program, 3 sessions/week, for 9 weeks. Exercises focused on balance, walking, strength and functional activities. Functional effects were assessed by Six Minute Walking Test (6MWT), Five Time Sit to Stand Test (FTSST), Berg Balance Scale (BBS), Sit and Reach Test (SRT), and Timed Up and Go test (TUG). Motor impairment and disability were assessed using the Unified Parkinson's Disease Rating Scale - part III (UPDRS-III) and the Hoehn and Yahr Scale, respectively. Non-motor symptoms were evaluated by PD Fatigue Scale (PFS), Beck Depression Inventory II (BDI-II) and PD Quality of life scale, 8 items (PDQ-8). RESULTS: A significant decrease in resting HR (67.55 ± 10.85 vs 70.22 ± 12.34 bpm, p < 0.05) and a significant increase in walked distance (p < 0.0005) were observed. A significant impairment of the muscles strength was noted (FTSST, p < 0.05). BBS showed a significant increase in balance abilities (p < 0.0005) and safety with mobility (TUG, p < 0.005) was enhanced. Finally, a significant improvement in motor and non-motor symptoms was detected: UPDRS-III (p < 0.00005), PFS (p < 0.005), BDI-II (p < 0.05) and PDQ-8 (p < 0.05). CONCLUSIONS: A tailored exercise program in PDpatients could be effective as an adjunct to conventional therapy on improving daily activities, motor and non-motor symptoms, with better QoL.
Authors: Miriam R Rafferty; Peter N Schmidt; Sheng T Luo; Kan Li; Connie Marras; Thomas L Davis; Mark Guttman; Fernando Cubillos; Tanya Simuni Journal: J Parkinsons Dis Date: 2017 Impact factor: 5.568
Authors: Joseph H Friedman; James C Beck; Kelvin L Chou; Gracia Clark; Christopher P Fagundes; Christopher G Goetz; Karen Herlofson; Benzi Kluger; Lauren B Krupp; Anthony E Lang; Jao-Shin Lou; Laura Marsh; Anne Newbould; Daniel Weintraub Journal: NPJ Parkinsons Dis Date: 2016-01-14