| Literature DB >> 25318599 |
Christina M McSweeney1, Vera M Foley, Gerard P McGlacken.
Abstract
The asymmetric alkylation of ketones represents a fundamental transformation in organic chemistry. Chiral auxiliaries have been used almost exclusively for this transformation. Herein we describe a strategy for the generation of enantiomerically enriched α-alkylated ketones up to an er of 83 : 17, using a chiral ligand protocol.Entities:
Mesh：
Substances：
Year: 2014 PMID： 25318599 DOI： 10.1039/c4cc06895e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222