Literature DB >> 2531790

Increased interleukin-1 beta (IL-1 beta) concentration in gingival tissue from periodontitis patients.

J Hönig, C Rordorf-Adam, C Siegmund, W Wiedemann, F Erard.   

Abstract

Human gingival tissues from periodontitis patients were found to contain from 126 fg/mg to 2161 fg/mg interleukin-1 beta as determined by a sensitive enzyme linked immunoassay. No IL-1 beta could be found in normal gingival tissue. This finding may have important consequences relevant to connective tissue destruction and episodes of alveolar bone resorption characteristic of chronic periodontitis.

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Year:  1989        PMID: 2531790     DOI: 10.1111/j.1600-0765.1989.tb00883.x

Source DB:  PubMed          Journal:  J Periodontal Res        ISSN: 0022-3484            Impact factor:   4.419


  30 in total

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9.  Interleukin-8 is a major neutrophil chemotactic factor derived from cultured human gingival fibroblasts stimulated with interleukin-1 beta or tumor necrosis factor alpha.

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10.  Interleukin-1 beta induces expression of cyclooxygenase-2 mRNA in human gingival fibroblasts.

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