Literature DB >> 25317004

Postmenopausal choriocarcinoma: A rare case report.

Sunil K Samal1, Setu Rathod1, Seetesh Ghose1.   

Abstract

Choriocarcinoma is a highly malignant epithelial tumor originating from trophoblast. It primarily occurs during the fertile period. Postmenopausal uterine choriocarcinoma is very rare. We present a case of choriocarcinoma in a postmenopausal lady developing 5 years after menopause. She presented with heavy postmenopausal bleeding along with passage of vesicles per vaginum. Serum beta-hCG was 96,484 mIU/ml. Emergency abdominal hysterectomy with bilateral salpingo-ooperectomy was done due to intractable bleeding following suction and evacuation. Histopathology revealed uterine choriocarcinoma. She was treated with EMACO regimen following which her beta-hCG returned to normal in five cycles. The patient is under regular follow-up and is doing well.

Entities:  

Keywords:  Uterine choricarcinoma; beta-hCG; postmenopausal bleeding

Year:  2014        PMID: 25317004      PMCID: PMC4195191          DOI: 10.4103/0976-7800.141229

Source DB:  PubMed          Journal:  J Midlife Health


  12 in total

1.  Carcinosarcoma of the uterus associated with a nongestational choriocarcinoma.

Authors:  H M Khuu; C P Crisco; L Kilgore; W H Rodgers; M G Conner
Journal:  South Med J       Date:  2000-02       Impact factor: 0.954

2.  Postmenopausal choriocarcinoma: a case report.

Authors:  Mădălina Marcu; Alina Chefani; Maria Sajin
Journal:  Rom J Morphol Embryol       Date:  2005       Impact factor: 1.033

3.  Primary non-gestational choriocarcinoma of the uterine cervix: a case report.

Authors:  Izildinha Maestá; Odair Carlito Michelin; Paulo Traiman; Paula Hokama; Marilza Vieira Cunha Rudge
Journal:  Gynecol Oncol       Date:  2005-07       Impact factor: 5.482

4.  A case of uterine choriocarcinoma with spontaneous rupture twenty-three years following the antecedent pregnancy.

Authors:  T Okamoto; S Nomura; T Nakanishi; S Yamada; Y Tomoda
Journal:  J Obstet Gynaecol Res       Date:  1997-04       Impact factor: 1.730

Review 5.  Gestational trophoblastic disease II: classification and management of gestational trophoblastic neoplasia.

Authors:  John R Lurain
Journal:  Am J Obstet Gynecol       Date:  2010-08-24       Impact factor: 8.661

6.  Gestational trophoblastic disease in women aged 50 or more.

Authors:  N Tsukamoto; T Iwasaka; Y Kashimura; H Uchino; M Kashimura; T Matsuyama
Journal:  Gynecol Oncol       Date:  1985-01       Impact factor: 5.482

7.  Establishing a germ cell origin for metastatic tumors using OCT4 immunohistochemistry.

Authors:  Liang Cheng
Journal:  Cancer       Date:  2004-11-01       Impact factor: 6.860

8.  Uterine gestational choriocarcinoma developing after a long latent period in a postmenopausal woman: the value of DNA polymorphism studies.

Authors:  Ciaran J O'Neill; Fionnuala Houghton; Jacqui Clarke; W Glenn McCluggage
Journal:  Int J Surg Pathol       Date:  2008-04       Impact factor: 1.271

9.  The impact of molecular genetic diagnosis on the management of women with hCG-producing malignancies.

Authors:  Rosemary A Fisher; Philip M Savage; Caitriona MacDermott; Jane Hook; Neil J Sebire; Iain Lindsay; Michael J Seckl
Journal:  Gynecol Oncol       Date:  2007-10-22       Impact factor: 5.482

10.  Primary non-gestational uterine cervical choriocarcinoma with metaplastic transformation from squamous cells.

Authors:  Bandit Chumworathayi; Pilaiwan Kleebkaow
Journal:  Asian Pac J Cancer Prev       Date:  2007 Oct-Dec
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  1 in total

1.  Pure nongestational uterine choriocarcinoma in postmenopausal women: a case report with literature review.

Authors:  Linping Wang; Yunzhe Wan; Yue Sun; Xiang Zhang; Xiaobo Cheng; Meijing Wu; Guoyan Liu
Journal:  Cancer Biol Ther       Date:  2019-05-27       Impact factor: 4.742

  1 in total

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