Literature DB >> 25316764

Incidence of narcotic abuse during pregnancy in northwestern Ontario: three-year prospective cohort study.

Len Kelly1, John Guilfoyle2, Joe Dooley2, Irwin Antone2, Lianne Gerber-Finn2, Roisin Dooley3, Nicole Brunton4, Kara Kakegamuck5, Jill Muileboom6, Wilma Hopman7, Helen Cromarty8, Barb Linkewich9, Jennifer Maki10.   

Abstract

OBJECTIVE: To document the incidence and outcomes of narcotic use during pregnancy in northwestern Ontario.
DESIGN: Three-year prospective cohort study.
SETTING: Sioux Lookout and surrounding communities in northwestern Ontario. PARTICIPANTS: A total of 1206 consecutive births in a catchment area of 28 000 First Nations patients. MAIN OUTCOME MEASURES: Incidence of narcotic use, and maternal and neonatal outcomes.
RESULTS: Incidence of narcotic use in pregnancy has risen to 28.6% (P < .001) and incidence of neonatal abstinence syndrome has fallen to 18.0% of narcotic-exposed births (P = .003). Daily intravenous drug use is now a common pattern of abuse.
CONCLUSION: Narcotic abuse in pregnancy has dramatically increased in northwestern Ontario. Neonatal outcomes have improved as a result of a family medicine-based prenatal and obstetric program that includes a narcotic replacement and tapering program. Copyright© the College of Family Physicians of Canada.

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Year:  2014        PMID： 25316764      PMCID： PMC4196835     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  10 in total

1.  Influence of site differences between urban and rural American and Central European opioid-dependent pregnant women and neonatal outcome characteristics.

Authors:  Andjela Baewert; Reinhold Jagsch; Bernadette Winklbaur; Gerda Kaiser; Kenneth Thau; Annemarie Unger; Constantin Aschauer; Manfred Weninger; Verena Metz
Journal:  Eur Addict Res       Date:  2012-02-21       Impact factor: 3.015

2.  Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone.

Authors:  Irfan A Dhalla; Muhammad M Mamdani; Marco L A Sivilotti; Alex Kopp; Omar Qureshi; David N Juurlink
Journal:  CMAJ       Date:  2009-12-07       Impact factor: 8.262

Review 3.  The occasional management of narcotic exposure in neonates.

Authors:  Len Kelly; Bryanne Minty; Sharen Madden; Joe Dooley; Irwin Antone
Journal:  Can J Rural Med       Date:  2011

4.  Comparison of methadone and slow-release morphine maintenance in pregnant addicts.

Authors:  G Fischer; R Jagsch; H Eder; W Gombas; P Etzersdorfer; K Schmidl-Mohl; C Schatten; M Weninger; H N Aschauer
Journal:  Addiction       Date:  1999-02       Impact factor: 6.526

5.  Narcotic-exposed neonates in a First Nations population in northwestern Ontario: incidence and implications.

Authors:  Len Kelly; Joe Dooley; Helen Cromarty; Bryanne Minty; Alanna Morgan; Sharen Madden; Wilma Hopman
Journal:  Can Fam Physician       Date:  2011-11       Impact factor: 3.275

6.  Neonatal abstinence syndrome after methadone or buprenorphine exposure.

Authors:  Hendrée E Jones; Karol Kaltenbach; Sarah H Heil; Susan M Stine; Mara G Coyle; Amelia M Arria; Kevin E O'Grady; Peter Selby; Peter R Martin; Gabriele Fischer
Journal:  N Engl J Med       Date:  2010-12-09       Impact factor: 91.245

7.  Facilitating medical withdrawal from opiates in rural Ontario.

Authors:  N Kiepek; L Hancock; D Toppozini; H Cromarty; A Morgan; L Kelly
Journal:  Rural Remote Health       Date:  2012-10-23       Impact factor: 1.759

8.  Neonatal abstinence syndrome clinical practice guidelines for Ontario.

Authors:  Kimberly Dow; Alice Ordean; Jodie Murphy-Oikonen; Jodie Pereira; Gideon Koren; Henry Roukema; Peter Selby; Ruth Turner
Journal:  J Popul Ther Clin Pharmacol       Date:  2012-11-23

Review 9.  Maintenance agonist treatments for opiate-dependent pregnant women.

Authors:  Silvia Minozzi; Laura Amato; Cristina Bellisario; Marica Ferri; Marina Davoli
Journal:  Cochrane Database Syst Rev       Date:  2013-12-23

10.  Predicting treatment for neonatal abstinence syndrome in infants born to women maintained on opioid agonist medication.

Authors:  Karol Kaltenbach; Amber M Holbrook; Mara G Coyle; Sarah H Heil; Amy L Salisbury; Susan M Stine; Peter R Martin; Hendrée E Jones
Journal:  Addiction       Date:  2012-11       Impact factor: 6.526
  10 in total
  10 in total

Review 1.  Community-associated methicillin-resistant Staphylococcus aureus infection: Literature review and clinical update.

Authors:  Kassandra Loewen; Yoko Schreiber; Mike Kirlew; Natalie Bocking; Len Kelly
Journal:  Can Fam Physician       Date:  2017-07       Impact factor: 3.275

2.  Narcotic tapering in pregnancy using long-acting morphine: an 18-month prospective cohort study in northwestern Ontario.

Authors:  Roisin Dooley; Joe Dooley; Irwin Antone; John Guilfoyle; Lianne Gerber-Finn; Kara Kakekagumick; Helen Cromarty; Wilma Hopman; Jill Muileboom; Nicole Brunton; Len Kelly
Journal:  Can Fam Physician       Date:  2015-02       Impact factor: 3.275

3.  First Nations hepatitis C virus infections: Six-year retrospective study of on-reserve rates of newly reported infections in northwestern Ontario.

Authors:  Janet Gordon; Natalie Bocking; Kathy Pouteau; Terri Farrell; Gareth Ryan; Len Kelly
Journal:  Can Fam Physician       Date:  2017-11       Impact factor: 3.275

4.  Opioid use during pregnancy: a population-based cohort study.

Authors:  Jamie Falk; Matthew Dahl; Colette B Raymond; Dan Chateau; Alan Katz; Christine Leong; Shawn Bugden
Journal:  CMAJ Open       Date:  2017-06-26

5.  Addiction in the family: Two Indigenous families overcoming barriers to opioid agonist therapy.

Authors:  Karen Lawford; Adam Newman
Journal:  Can Fam Physician       Date:  2022-05       Impact factor: 3.025

6.  "People in regular society don't think you can be a good mother and have a substance use problem": Participatory action research with women with substance use in pregnancy.

Authors:  Kali Gartner; Kelly Elliott; Michelle Smith; Hilary Pearson; Georgia Hunt; Ruth Elwood Martin
Journal:  Can Fam Physician       Date:  2018-07       Impact factor: 3.275

7.  Differences in hospital length of stay between neonates exposed to buprenorphine versus methadone in utero: A retrospective chart review.

Authors:  Sarah Fernandez; Teresa Bruni; Lisa Bishop; Roxanne Turuba; Brieanne Olibris; Naana Afua Jumah
Journal:  Paediatr Child Health       Date:  2018-07-17       Impact factor: 2.253

8.  Observational study of the safety of buprenorphine+naloxone in pregnancy in a rural and remote population.

Authors:  Naana Afua Jumah; Craig Edwards; Jazmyn Balfour-Boehm; Kassandra Loewen; Joseph Dooley; Lianne Gerber Finn; Len Kelly
Journal:  BMJ Open       Date:  2016-10-31       Impact factor: 2.692

9.  High Incidence of Invasive Group A Streptococcal Infections in Remote Indigenous Communities in Northwestern Ontario, Canada.

Authors:  Natalie Bocking; Cai-Lei Matsumoto; Kassandra Loewen; Sarah Teatero; Alex Marchand-Austin; Janet Gordon; Nahuel Fittipaldi; Allison McGeer
Journal:  Open Forum Infect Dis       Date:  2016-12-07       Impact factor: 3.835

Review 10.  Rural, Pregnant, and Opioid Dependent: A Systematic Review.

Authors:  Naana Afua Jumah
Journal:  Subst Abuse       Date:  2016-06-20
  10 in total

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