Literature DB >> 25315804

'Diabetic ketoacidosis may not always be the answer…'.

Deirdre Philbin1, Edina Moylett1.   

Abstract

We present the interesting case of a 9-year-old boy with type 1 diabetes mellitus. He presented to the emergency department extremely unwell and the diagnosis of diabetic ketoacidosis was promptly performed. He was started on the local diabetic ketoacidosis (DKA) protocol, but his recovery remained slow. The possibility of an underlying pathology was later addressed and led to the diagnosis of primary adrenal insufficiency. This case highlights the difficulty in diagnosis of childhood Addison's disease due to its vague and non-specific symptoms and the importance of a high degree of clinical suspicion. This case also highlights the existence of autoimmune polyendocrine syndromes and the ongoing need to increase awareness and screening of these conditions. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25315804      PMCID: PMC4202087          DOI: 10.1136/bcr-2014-206344

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

Review 1.  Autoimmune polyendocrine syndromes.

Authors:  George S Eisenbarth; Peter A Gottlieb
Journal:  N Engl J Med       Date:  2004-05-13       Impact factor: 91.245

2.  Primary adrenal insufficiency in childhood and adolescence: advances in diagnosis and management.

Authors:  P J Simm; C M McDonnell; M R Zacharin
Journal:  J Paediatr Child Health       Date:  2004-11       Impact factor: 1.954

3.  Addison's disease presenting with an acute abdomen and complicated by cardiomyopathy.

Authors:  E J Wiltshire; R Wilson; K C Pringle
Journal:  J Paediatr Child Health       Date:  2004-11       Impact factor: 1.954

4.  Rare presentation of shock and acute mesenteric ischaemia secondary to acute adrenal insufficiency in an 11-year-old male.

Authors:  Maria B Roldan-Martin; Alejandro Rodriguez-Ogando; Amelia C Sanchez-Galindo; Alberto Parente-Hernandez; Vanessa Luengo-Herrero; Cesar Sanchez-Sanchez
Journal:  J Paediatr Child Health       Date:  2012-09-13       Impact factor: 1.954

Review 5.  Adrenal insufficiency: still a cause of morbidity and death in childhood.

Authors:  Dorothy I Shulman; Mark R Palmert; Stephen F Kemp
Journal:  Pediatrics       Date:  2007-01-22       Impact factor: 7.124

6.  Presentation of primary adrenal insufficiency in childhood.

Authors:  Susan Hsieh; Perrin C White
Journal:  J Clin Endocrinol Metab       Date:  2011-04-06       Impact factor: 5.958

7.  Conscious level in children with diabetic ketoacidosis is related to severity of acidosis and not to blood glucose concentration.

Authors:  Julie A Edge; Yvonne Roy; Andrea Bergomi; Nuala P Murphy; Martha E Ford-Adams; Ken K Ong; David B Dunger
Journal:  Pediatr Diabetes       Date:  2006-02       Impact factor: 4.866

  7 in total

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