Literature DB >> 25314070

A new TIPE of phosphoinositide regulator in cancer.

Larissa S Moniz1, Bart Vanhaesebroeck2.   

Abstract

Specific phosphoinositide lipids promote cell growth and cancer. In this issue of Cancer Cell, Fayngerts and colleagues demonstrate that the TIPE3 protein enhances PtdIns(4,5)P2 and PtdIns(3,4,5)P3, is overexpressed in certain cancers, and promotes tumorigenesis. TIPE3 can act as a lipid transfer protein and may constitute a novel phosphoinositide metabolism regulator.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 25314070     DOI： 10.1016/j.ccell.2014.09.017

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  5 in total

1.  Adenovirus-mediated TIPE2 overexpression inhibits gastric cancer metastasis via reversal of epithelial-mesenchymal transition.

Authors:  H Yin; X Huang; M Tao; Q Hu; J Qiu; W Chen; J Wu; Y Xie
Journal:  Cancer Gene Ther       Date:  2017-02-10       Impact factor: 5.987

Review 2.  Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer.

Authors:  Diego Peretti; SoHui Kim; Roberta Tufi; Sima Lev
Journal:  Front Cell Dev Biol       Date:  2020-01-23

3.  TIPE3 promotes non-small cell lung cancer progression via the protein kinase B/extracellular signal-regulated kinase 1/2-glycogen synthase kinase 3β-β-catenin/Snail axis.

Authors:  Qiang Li; Dongmei Yu; Zhengyuan Yu; Qian Gao; Ruifang Chen; Lin Zhou; Rong Wang; Yan Li; Yulan Qian; Jun Zhao; Rafael Rosell; Min Tao; Yufeng Xie; Chun Xu
Journal:  Transl Lung Cancer Res       Date:  2021-02

4.  TIPE1 Suppresses Growth and Metastasis of Ovarian Cancer.

Authors:  Zhenyu Zhang; Minghui Chang; Xingguo Song; Kangyu Wang; Wenjuan Sun; Hongxin Ma; Xiaohui Yan; Yuhong Sun; Xianrang Song; Li Xie
Journal:  J Oncol       Date:  2021-06-03       Impact factor: 4.375

5.  Overexpression of Tumour Necrosis Factor-α-Induced Protein 8 is Associated with Prognosis in Colon Cancer.

Authors:  Xingqi Zhang; Zequn Li; Yuqi Sun; Gan Liu; Xiaodong Liu; Yanbing Zhou
Journal:  Cancer Manag Res       Date:  2021-05-18       Impact factor: 3.989
  5 in total

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