Eric T Payne1, Cecil D Hahn. 1. aDivision of Neurology, The Hospital for Sick Children bDepartment of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
Abstract
PURPOSE OF REVIEW: To discuss the use of continuous video-electroencephalographic (cEEG) monitoring among critically ill children at risk for electrographic seizures and status epilepticus. RECENT FINDINGS: Recent reports have demonstrated the growing, but heterogeneous, use of cEEG monitoring among North American pediatric institutions, and provided evidence for the high prevalence of subclinical seizures, particularly among encephalopathic patients with acute brain injury. Increasing seizure burden and status epilepticus have been shown to be independently associated with worse short-term and long-term outcomes. SUMMARY: Certain high-risk children frequently experience electrographic seizures and status epilepticus, often without clinical signs, necessitating the use of cEEG monitoring for their diagnosis and management. Although an increasing electrographic seizure burden and status epilepticus are independently associated with worse outcome, further studies are needed to determine whether aggressive use of antiepileptic drugs to reduce seizure burden can improve outcome.
PURPOSE OF REVIEW: To discuss the use of continuous video-electroencephalographic (cEEG) monitoring among critically ill children at risk for electrographic seizures and status epilepticus. RECENT FINDINGS: Recent reports have demonstrated the growing, but heterogeneous, use of cEEG monitoring among North American pediatric institutions, and provided evidence for the high prevalence of subclinical seizures, particularly among encephalopathic patients with acute brain injury. Increasing seizure burden and status epilepticus have been shown to be independently associated with worse short-term and long-term outcomes. SUMMARY: Certain high-risk children frequently experience electrographic seizures and status epilepticus, often without clinical signs, necessitating the use of cEEG monitoring for their diagnosis and management. Although an increasing electrographic seizure burden and status epilepticus are independently associated with worse outcome, further studies are needed to determine whether aggressive use of antiepileptic drugs to reduce seizure burden can improve outcome.
Authors: Daniel L Kenney-Jung; Annamaria Vezzani; Robert J Kahoud; Reghann G LaFrance-Corey; Mai-Lan Ho; Theresa Wampler Muskardin; Elaine C Wirrell; Charles L Howe; Eric T Payne Journal: Ann Neurol Date: 2016-11-14 Impact factor: 10.422
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