Shengli Lin1, Rong Li1, Hongbin Chi1, Shuo Huang1, Hua Zhang2, Xiaoying Zheng1, Ping Liu1, Jie Qiao3. 1. Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China. 2. Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, People's Republic of China. 3. Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China. Electronic address: jie.qiao@263.net.
Abstract
OBJECTIVE: To explore the effect of ABO blood type on ovarian reserve in Chinese women. DESIGN: Retrospective analysis. SETTING: University-affiliated IVF center. PATIENT(S): The retrospective analysis involved 35,479 women who underwent in vitro fertilization and embryo transfer (IVF-ET) cycles between 2006 and 2012. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The association between ABO blood types and diminished ovarian reserve (DOR). RESULT(S): Among 35,479 Chinese women, 11,395 (32.12%) had blood type B, 10,583 (29.83%) had blood type O, 9,861 (27.79%) had blood type A, and 3,640 (10.26%) had blood type AB. There was a statistically significantly higher percentage of blood type O among those with follicle-stimulating hormone (FSH) levels ≤10 IU/L compared with those with FSH levels >10 IU/L. Conversely, among the women with DOR, there was statistically significantly higher percentage of those with blood types B and AB. Blood type A was not associated with DOR occurrence. Multivariate logistic regression analysis showed that blood type O was statistically significantly less often associated with DOR occurrence, whereas the B antigen (blood type B or AB) was statistically significantly associated with an increased risk of DOR. CONCLUSION(S): Our results have shown that there is an association between ABO blood type and DOR occurrence in Chinese women. Women with blood type O were statistically significantly less likely to have DOR, whereas those with B antigen (blood type B or AB) were statistically significantly more likely to have DOR. Blood type A was not associated with ovarian reserve.
OBJECTIVE: To explore the effect of ABO blood type on ovarian reserve in Chinese women. DESIGN: Retrospective analysis. SETTING: University-affiliated IVF center. PATIENT(S): The retrospective analysis involved 35,479 women who underwent in vitro fertilization and embryo transfer (IVF-ET) cycles between 2006 and 2012. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The association between ABO blood types and diminished ovarian reserve (DOR). RESULT(S): Among 35,479 Chinese women, 11,395 (32.12%) had blood type B, 10,583 (29.83%) had blood type O, 9,861 (27.79%) had blood type A, and 3,640 (10.26%) had blood type AB. There was a statistically significantly higher percentage of blood type O among those with follicle-stimulating hormone (FSH) levels ≤10 IU/L compared with those with FSH levels >10 IU/L. Conversely, among the women with DOR, there was statistically significantly higher percentage of those with blood types B and AB. Blood type A was not associated with DOR occurrence. Multivariate logistic regression analysis showed that blood type O was statistically significantly less often associated with DOR occurrence, whereas the B antigen (blood type B or AB) was statistically significantly associated with an increased risk of DOR. CONCLUSION(S): Our results have shown that there is an association between ABO blood type and DOR occurrence in Chinese women. Women with blood type O were statistically significantly less likely to have DOR, whereas those with B antigen (blood type B or AB) were statistically significantly more likely to have DOR. Blood type A was not associated with ovarian reserve.
Authors: Nigel Pereira; Anne P Hutchinson; Jennifer L Bender; Jovana P Lekovich; Rony T Elias; Zev Rosenwaks; Steven D Spandorfer Journal: J Assist Reprod Genet Date: 2015-05-03 Impact factor: 3.412
Authors: Khalid Awartani; Rahma Al Ghabshi; Hanan Al Shankiti; Mohamed Al Dossari; Serdar Coskun Journal: Ann Saudi Med Date: 2016-03-31 Impact factor: 1.526