Literature DB >> 2531285

Transfection of a human gene that corrects the Lec1 glycosylation defect: evidence for transfer of the structural gene for N-acetylglucosaminyltransferase I.

R Kumar1, P Stanley.   

Abstract

Chinese hamster ovary (CHO) glycosylation mutants provide an approach to cloning mammalian glycosyltransferases by transfection and gene rescue. In this paper, complementation of the lec1 CHO mutation by human DNA is described. Lec1 transfectants expressed human N-acetylglucosaminyltransferase I (GlcNAc-TI) activity and possessed common human DNA fragments. Cloning of GlcNAc-TI should therefore be possible.

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Year:  1989        PMID： 2531285      PMCID： PMC363743          DOI： 10.1128/mcb.9.12.5713-5717.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  21 in total

1.  Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamine--glycoprotein N-acetylglucosaminyltransferase activity.

Authors:  P Stanley; S Narasimhan; L Siminovitch; H Schachter
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

2.  The chromic chloride method of coupling antigens to erythrocytes: definition of some important parameters.

Authors:  J W Goding
Journal:  J Immunol Methods       Date:  1976       Impact factor: 2.303

3.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

4.  Specific changes in the oligosaccharide moieties of VSV grown in different lectin-resistnat CHO cells.

Authors:  M A Robertson; J R Etchison; J S Robertson; D F Summers; P Stanley
Journal:  Cell       Date:  1978-03       Impact factor: 41.582

Review 5.  Analysis of the synthesis, intracellular sorting, and function of glycoproteins using a mammalian cell mutant with reversible glycosylation defects.

Authors:  M Krieger; P Reddy; K Kozarsky; D Kingsley; L Hobbie; M Penman
Journal:  Methods Cell Biol       Date:  1989       Impact factor: 1.441

6.  Stable expression of blood group H determinants and GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase in mouse cells after transfection with human DNA.

Authors:  L K Ernst; V P Rajan; R D Larsen; M M Ruff; J B Lowe
Journal:  J Biol Chem       Date:  1989-02-25       Impact factor: 5.157

7.  A cloned human DNA restriction fragment determines expression of a GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase in transfected cells. Evidence for isolation and transfer of the human H blood group locus.

Authors:  V P Rajan; R D Larsen; S Ajmera; L K Ernst; J B Lowe
Journal:  J Biol Chem       Date:  1989-07-05       Impact factor: 5.157

8.  Selection and characterization of Chinese hamster ovary cells resistant to the cytotoxicity of lectins.

Authors:  P Stanley; L Siminovitch
Journal:  In Vitro       Date:  1976-03

9.  The GDP-fucose:N-acetylglucosaminide 3-alpha-L-fucosyltransferases of LEC11 and LEC12 Chinese hamster ovary mutants exhibit novel specificities for glycolipid substrates.

Authors:  D R Howard; M Fukuda; M N Fukuda; P Stanley
Journal:  J Biol Chem       Date:  1987-12-15       Impact factor: 5.157

10.  DNA-mediated transformation of N-acetylglucosaminyltransferase I activity into an enzyme deficient cell line.

Authors:  J Ripka; M Pierce; N Fregien
Journal:  Biochem Biophys Res Commun       Date:  1989-03-15       Impact factor: 3.575
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  14 in total

1.  O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1.

Authors:  Nadia A Rana; Aleksandra Nita-Lazar; Hideyuki Takeuchi; Shinako Kakuda; Kelvin B Luther; Robert S Haltiwanger
Journal:  J Biol Chem       Date:  2011-07-08       Impact factor: 5.157

Review 2.  Mouse models for congenital disorders of glycosylation.

Authors:  Christian Thiel; Christian Körner
Journal:  J Inherit Metab Dis       Date:  2011-02-24       Impact factor: 4.982

3.  More than just sugars: Conserved oligomeric Golgi complex deficiency causes glycosylation-independent cellular defects.

Authors:  Jessica B Blackburn; Tetyana Kudlyk; Irina Pokrovskaya; Vladimir V Lupashin
Journal:  Traffic       Date:  2018-04-24       Impact factor: 6.215

4.  Polyoma and hamster papovavirus large T antigen-mediated replication of expression shuttle vectors in Chinese hamster ovary cells.

Authors:  M Heffernan; J W Dennis
Journal:  Nucleic Acids Res       Date:  1991-01-11       Impact factor: 16.971

5.  Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesis.

Authors:  B Yip; S H Chen; H Mulder; J W Höppener; H Schachter
Journal:  Biochem J       Date:  1997-01-15       Impact factor: 3.857

6.  Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation.

Authors:  R Kumar; J Yang; R D Larsen; P Stanley
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

7.  Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates.

Authors:  E Ioffe; P Stanley
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

8.  Identification of minimum carbohydrate moiety in N-glycosylation sites of brain endothelial cell glycoprotein 96 for interaction with Escherichia coli K1 outer membrane protein A.

Authors:  Subramanian Krishnan; Nemani V Prasadarao
Journal:  Microbes Infect       Date:  2014-06-13       Impact factor: 2.700

9.  Dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150).

Authors:  Chanakha K Navaratnarajah; Sompong Vongpunsawad; Numan Oezguen; Thilo Stehle; Werner Braun; Takao Hashiguchi; Katsumi Maenaka; Yusuke Yanagi; Roberto Cattaneo
Journal:  J Biol Chem       Date:  2008-02-21       Impact factor: 5.157

10.  A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface.

Authors:  Sarah E Stewart; Sam A Menzies; Stephanie J Popa; Natalia Savinykh; Anna Petrunkina Harrison; Paul J Lehner; Kevin Moreau
Journal:  J Cell Sci       Date:  2017-08-03       Impact factor: 5.285
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