Literature DB >> 25312792

Short communication: Fc gamma receptors IIa and IIIa genetic polymorphisms do not predict HIV-1 disease progression in Kenyan women.

Julie F Weis1, R Scott McClelland, Walter Jaoko, Kishor N Mandaliya, Julie Overbaugh, Susan M Graham.   

Abstract

Genetic polymorphisms of the Fc gamma receptors (FcγR) IIa and IIIa have been implicated in the rate of HIV-1 disease progression, but results are inconsistent. We aimed to determine the association between these polymorphisms and disease progression in a cohort of HIV-1 seroconverters from Mombasa, Kenya. Neither FcγRIIa nor FcγRIIIa genotypes were predictive of set point viral load, viral load increase, CD4 decline, or HIV-1 disease progression (time to CD4 count <200 cells/mm(3), death, or treatment initiation). Our results suggest that FcγR polymorphisms might not be an important indicator of viral control and disease progression in this population.

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Year:  2014        PMID： 25312792      PMCID： PMC4348085          DOI： 10.1089/AID.2014.0209

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  27 in total

1.  Molecular basis for a polymorphism involving Fc receptor II on human monocytes.

Authors:  M R Clark; S B Clarkson; P A Ory; N Stollman; I M Goldstein
Journal:  J Immunol       Date:  1989-09-01       Impact factor: 5.422

Review 2.  Contribution of Fcgamma receptor IIIA gene 158V/F polymorphism and copy number variation to the risk of ACPA-positive rheumatoid arthritis.

Authors:  M M Thabet; T W J Huizinga; R B Marques; G Stoeken-Rijsbergen; A M Bakker; F A Kurreeman; S J White; R E M Toes; A H M van der Helm-van Mil
Journal:  Ann Rheum Dis       Date:  2008-11-19       Impact factor: 19.103

Review 3.  IgG Fc receptors.

Authors:  J V Ravetch; S Bolland
Journal:  Annu Rev Immunol       Date:  2001       Impact factor: 28.527

4.  Association of FCgamma receptor IIA (CD32) polymorphism with malarial anemia and high-density parasitemia in infants and young children.

Authors:  Collins Ouma; Christopher C Keller; Dorothy A Opondo; Tom Were; Richard O Otieno; Michael F Otieno; Alloys S S Orago; John M Ong'Echa; John M Vulule; Robert E Ferrell; Douglas J Perkins
Journal:  Am J Trop Med Hyg       Date:  2006-04       Impact factor: 2.345

5.  Injectable contraceptive use and genital ulcer disease during the early phase of HIV-1 infection increase plasma virus load in women.

Authors:  Ludo Lavreys; Jared M Baeten; Joan K Kreiss; Barbra A Richardson; Bhavna H Chohan; Wisal Hassan; Dana D Panteleeff; Kishorchandra Mandaliya; Jeckoniah O Ndinya-Achola; Julie Overbaugh
Journal:  J Infect Dis       Date:  2004-01-09       Impact factor: 5.226

6.  Fc receptor-mediated immune responses: new tools but increased complexity in HIV prevention.

Authors:  Diego A Vargas-Inchaustegui; Marjorie Robert-Guroff
Journal:  Curr HIV Res       Date:  2013-07       Impact factor: 1.581

7.  FcgammaRIIa genotype predicts progression of HIV infection.

Authors:  Donald N Forthal; Gary Landucci; Jay Bream; Lisa P Jacobson; Tran B Phan; Benjamin Montoya
Journal:  J Immunol       Date:  2007-12-01       Impact factor: 5.422

8.  Natural Killer cell-dependent and non-dependent anti-viral activity of 2-Cys Peroxiredoxin against HIV.

Authors:  Mohammed Asmal; Norman L Letvin; Ralf Geiben-Lynn
Journal:  Int Trends Immun       Date:  2013-10

9.  A single amino acid distinguishes the high-responder from the low-responder form of Fc receptor II on human monocytes.

Authors:  M R Clark; S G Stuart; R P Kimberly; P A Ory; I M Goldstein
Journal:  Eur J Immunol       Date:  1991-08       Impact factor: 5.532

10.  High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression.

Authors:  Bhawna Poonia; Gustavo H Kijak; C David Pauza
Journal:  PLoS One       Date:  2010-12-20       Impact factor: 3.240
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  7 in total

Review 1.  Antibody Functional Assays as Measures of Fc Receptor-Mediated Immunity to HIV - New Technologies and their Impact on the HIV Vaccine Field.

Authors:  Bruce D Wines; Hugh Billings; Milla R Mclean; Stephen J Kent; P Mark Hogarth
Journal:  Curr HIV Res       Date:  2017       Impact factor: 1.581

Review 2.  Association of Diverse Genotypes and Phenotypes of Immune Cells and Immunoglobulins With the Course of HIV-1 Infection.

Authors:  Liuzhe Li; Yan Liu; Miroslaw K Gorny
Journal:  Front Immunol       Date:  2018-11-26       Impact factor: 7.561

Review 3.  Effect of Fc Receptor Genetic Diversity on HIV-1 Disease Pathogenesis.

Authors:  Daniel E Geraghty; Christian W Thorball; Jacques Fellay; Rasmi Thomas
Journal:  Front Immunol       Date:  2019-05-09       Impact factor: 7.561

4.  FcγRIIIa receptor polymorphism influences NK cell mediated ADCC activity against HIV.

Authors:  Sneha Pramod Talathi; Nawaj Najir Shaikh; Sudhanshu Shekhar Pandey; Vandana Ashish Saxena; Megha Sunil Mamulwar; Madhuri Rajeev Thakar
Journal:  BMC Infect Dis       Date:  2019-12-16       Impact factor: 3.090

5.  FcγR Genetic Variation and HIV-1 Vaccine Efficacy: Context And Considerations.

Authors:  Ria Lassaunière; Caroline T Tiemessen
Journal:  Front Immunol       Date:  2021-12-15       Impact factor: 7.561

6.  FCGR3A gene duplication, FcγRIIb-232TT and FcγRIIIb-HNA1a associate with an increased risk of vertical acquisition of HIV-1.

Authors:  Joy Ebonwu; Ria Lassaunière; Maria Paximadis; Renate Strehlau; Glenda E Gray; Louise Kuhn; Caroline T Tiemessen
Journal:  PLoS One       Date:  2022-09-09       Impact factor: 3.752

7.  FCGR2A and FCGR3A Genotypes in Human Immunodeficiency Virus Mother-to-Child Transmission.

Authors:  Caitlin Milligan; Barbra A Richardson; Grace John-Stewart; Ruth Nduati; Julie Overbaugh
Journal:  Open Forum Infect Dis       Date:  2015-10-14       Impact factor: 3.835
  7 in total

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