Literature DB >> 25311173

Pharmacological management of hypertension in pregnancy.

Thomas R Easterling1.   

Abstract

Hypertension in pregnancy remains a significant public health problem. Pharmacological management of blood pressure in pregnancy is impacted by changes in maternal drug disposition and by the pharmacodynamic effects of specific agents. This article will review the impact of pregnancy on pathways of drug elimination and the associated clinical implications, the pharmacodynamic effects of specific drugs and classes of drugs in pregnancy, and the data to date on the impact of antihypertensive therapy on mothers and their fetuses.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  IUGR; antihypertensive; hypertension; preeclampsia; pregnancy

Mesh：

Substances：

Year:  2014        PMID： 25311173      PMCID： PMC4272602          DOI： 10.1053/j.semperi.2014.08.016

Source DB:  PubMed          Journal:  Semin Perinatol        ISSN： 0146-0005            Impact factor:   3.300


  28 in total

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Authors:  T R Easterling; T J Benedetti; B C Schmucker; S P Millard
Journal:  Obstet Gynecol       Date:  1990-12       Impact factor: 7.661

2.  Pharmacodynamics of clonidine therapy in pregnancy: a heterogeneous maternal response impacts fetal growth.

Authors:  Sophia Rothberger; Darcy Carr; Debra Brateng; Mary Hebert; Thomas R Easterling
Journal:  Am J Hypertens       Date:  2010-08-19       Impact factor: 2.689

3.  Antihypertensive therapy in pregnancy directed by noninvasive hemodynamic monitoring.

Authors:  T R Easterling; T J Benedetti; B C Schmucker; K L Carlson
Journal:  Am J Perinatol       Date:  1989-01       Impact factor: 1.862

4.  Oral nifedipine pharmacokinetics in pregnancy-induced hypertension.

Authors:  R R Prevost; S A Akl; W D Whybrew; B M Sibai
Journal:  Pharmacotherapy       Date:  1992       Impact factor: 4.705

5.  Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.

Authors:  Aram V Chobanian; George L Bakris; Henry R Black; William C Cushman; Lee A Green; Joseph L Izzo; Daniel W Jones; Barry J Materson; Suzanne Oparil; Jackson T Wright; Edward J Roccella
Journal:  Hypertension       Date:  2003-12-01       Impact factor: 10.190

6.  Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes.

Authors:  Hagay Orbach; Ilan Matok; Rafael Gorodischer; Eyal Sheiner; Sharon Daniel; Arnon Wiznitzer; Gideon Koren; Amalia Levy
Journal:  Am J Obstet Gynecol       Date:  2012-11-15       Impact factor: 8.661

7.  Nifedipine pharmacokinetics and pharmacodynamics during the immediate postpartum period in patients with preeclampsia.

Authors:  J R Barton; R R Prevost; D A Wilson; W D Whybrew; B M Sibai
Journal:  Am J Obstet Gynecol       Date:  1991-10       Impact factor: 8.661

Review 8.  Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.

Authors:  Ulrich M Zanger; Matthias Schwab
Journal:  Pharmacol Ther       Date:  2013-01-16       Impact factor: 12.310

9.  Clonidine pharmacokinetics in pregnancy.

Authors:  M L Buchanan; T R Easterling; D B Carr; D D Shen; L J Risler; W L Nelson; D R Mattison; M F Hebert
Journal:  Drug Metab Dispos       Date:  2008-12-30       Impact factor: 3.922

10.  Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study.

Authors:  M F Hebert; T R Easterling; B Kirby; D B Carr; M L Buchanan; T Rutherford; K E Thummel; D P Fishbein; J D Unadkat
Journal:  Clin Pharmacol Ther       Date:  2008-02-20       Impact factor: 6.903
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  9 in total

1.  Maternal Hypertension, Antihypertensive Medication Use, and Small for Gestational Age Births in the National Birth Defects Prevention Study, 1997-2011.

Authors:  Sarah C Fisher; Alissa R Van Zutphen; Paul A Romitti; Marilyn L Browne
Journal:  Matern Child Health J       Date:  2018-02

Review 2.  Treating Hypertension in Pregnancy.

Authors:  Dietmar Schlembach; Volker Homuth; Ralf Dechend
Journal:  Curr Hypertens Rep       Date:  2015-08       Impact factor: 5.369

3.  Effect of N-Acetyltransferase 2 Genotype on the Pharmacokinetics of Hydralazine During Pregnancy.

Authors:  Lyrialle W Han; Rachel J Ryu; Michael Cusumano; Thomas R Easterling; Brian R Phillips; Linda J Risler; Danny D Shen; Mary F Hebert
Journal:  J Clin Pharmacol       Date:  2019-06-30       Impact factor: 3.126

Review 4.  Hypertension in CKD Pregnancy: a Question of Cause and Effect (Cause or Effect? This Is the Question).

Authors:  Giorgina Barbara Piccoli; Gianfranca Cabiddu; Rossella Attini; Silvia Parisi; Federica Fassio; Valentina Loi; Martina Gerbino; Marilisa Biolcati; Antonello Pani; Tullia Todros
Journal:  Curr Hypertens Rep       Date:  2016-04       Impact factor: 5.369

Review 5.  Regulators of G protein signaling in cardiovascular function during pregnancy.

Authors:  Katherine J Perschbacher; Guorui Deng; Rory A Fisher; Katherine N Gibson-Corley; Mark K Santillan; Justin L Grobe
Journal:  Physiol Genomics       Date:  2018-04-27       Impact factor: 3.107

6.  Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach.

Authors:  Liuting Zeng; Kailin Yang; Jinwen Ge
Journal:  Sci Rep       Date:  2017-12-04       Impact factor: 4.379

7.  Hypertension among women of reproductive age: Impact of 2017 American College of Cardiology/American Heart Association high blood pressure guideline.

Authors:  Han-Yang Chen; Suneet P Chauhan
Journal:  Int J Cardiol Hypertens       Date:  2019-05-07

8.  Adrb2 controls glucose homeostasis by developmental regulation of pancreatic islet vasculature.

Authors:  Alexis M Ceasrine; Eugene E Lin; David N Lumelsky; Radhika Iyer; Rejji Kuruvilla
Journal:  Elife       Date:  2018-10-10       Impact factor: 8.140

9.  Correlation between the expression of inflammatory cytokines IL-6, TNF-α and hs-CRP and unfavorable fetal outcomes in patients with pregnancy-induced hypertension.

Authors:  Dehua Kong; Hui Wang; Yan Liu; Hongjun Li; Hongyan Wang; Peng Zhu
Journal:  Exp Ther Med       Date:  2018-07-02       Impact factor: 2.447
  9 in total

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