Literature DB >> 25308898

Construction of erythrinane skeleton via Pd(0)-catalyzed intramolecular dearomatization of para-aminophenols.

Ren-Qi Xu1, Qing Gu, Wen-Ting Wu, Zhuo-An Zhao, Shu-Li You.   

Abstract

A novel Pd(0)-catalyzed intramolecular arylative dearomatization of para-aminophenol derivatives is described. In the presence of 1.25 mol % [Pd(C3H5)Cl]2 and 3.75 mol % RuPhos, the arylative dearomatization reaction proceeds smoothly for a broad range of substrates, offering an efficient synthetic route to erythrinane derivatives in excellent yields.

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Year:  2014        PMID: 25308898     DOI: 10.1021/ja508645j

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  4 in total

1.  A Short Synthesis of (±)-3-Demethoxyerythratidinone by Ligand-Controlled Selective Heck Cyclization of Equilibrating Enamines.

Authors:  Emma E Blackham; Kevin I Booker-Milburn
Journal:  Angew Chem Int Ed Engl       Date:  2017-05-04       Impact factor: 15.336

2.  Total synthesis of (+)-spiroindimicin A and congeners unveils their antiparasitic activity.

Authors:  Zhen Zhang; Sneha Ray; Leah Imlay; Lauren T Callaghan; Hanspeter Niederstrasser; Prema Latha Mallipeddi; Bruce A Posner; Dawn M Wetzel; Margaret A Phillips; Myles W Smith
Journal:  Chem Sci       Date:  2021-06-30       Impact factor: 9.825

3.  Synthesis of tetracyclic indolin-3-ones through Pd-catalyzed intramolecular deacetylative dearomatization of 3-acetoxy-indoles.

Authors:  Ren-Xiao Liang; Ke Wang; Ling-Jie Song; Wei-Jian Sheng; Yi-Xia Jia
Journal:  RSC Adv       Date:  2019-05-07       Impact factor: 3.361

4.  Organocatalytic asymmetric chlorinative dearomatization of naphthols.

Authors:  Qin Yin; Shou-Guo Wang; Xiao-Wei Liang; De-Wei Gao; Jun Zheng; Shu-Li You
Journal:  Chem Sci       Date:  2015-04-27       Impact factor: 9.825

  4 in total

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