Literature DB >> 25308485

PCR based determination of mitochondrial DNA copy number in multiple species.

John P Rooney1, Ian T Ryde, Laurie H Sanders, Evan H Howlett, Meryl D Colton, Kaylyn E Germ, Greg D Mayer, J Timothy Greenamyre, Joel N Meyer.   

Abstract

Mitochondrial DNA (mtDNA) copy number is a critical component of overall mitochondrial health. In this chapter, we describe methods for isolation of both mtDNA and nuclear DNA (nucDNA) and measurement of their respective copy numbers using quantitative PCR. Methods differ depending on the species and cell type of the starting material and availability of specific PCR reagents.

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Year:  2015        PMID： 25308485      PMCID： PMC4312664          DOI： 10.1007/978-1-4939-1875-1_3

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  21 in total

1.  Measurement of mitochondrial DNA copy number.

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Journal:  Methods Mol Biol       Date:  2012

Review 2.  Mitochondrial DNA depletion syndromes--many genes, common mechanisms.

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Review 3.  Mitochondrial DNA mutations in disease and aging.

Authors:  Douglas C Wallace
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Review 4.  Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers.

Authors:  Man Yu
Journal:  Life Sci       Date:  2011-06-13       Impact factor: 5.037

Review 5.  Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number.

Authors:  Christopher T Campbell; Jill E Kolesar; Brett A Kaufman
Journal:  Biochim Biophys Acta       Date:  2012-03-21

Review 6.  A mitochondrial etiology of Alzheimer and Parkinson disease.

Authors:  Pinar Coskun; Joanne Wyrembak; Samual E Schriner; Hsiao-Wen Chen; Christine Marciniack; Frank Laferla; Douglas C Wallace
Journal:  Biochim Biophys Acta       Date:  2011-08-16

Review 7.  Defects in mitochondrial DNA replication and human disease.

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Journal:  Crit Rev Biochem Mol Biol       Date:  2012 Jan-Feb       Impact factor: 8.250

8.  Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR.

Authors:  Amy M Furda; Amanda Smith Bess; Joel N Meyer; Bennett Van Houten
Journal:  Methods Mol Biol       Date:  2012

9.  Developmental exposure to second-hand smoke increases adult atherogenesis and alters mitochondrial DNA copy number and deletions in apoE(-/-) mice.

Authors:  Jessica L Fetterman; Melissa Pompilius; David G Westbrook; Dale Uyeminami; Jamelle Brown; Kent E Pinkerton; Scott W Ballinger
Journal:  PLoS One       Date:  2013-06-25       Impact factor: 3.240

10.  Placental mitochondrial DNA content and particulate air pollution during in utero life.

Authors:  Bram G Janssen; Elke Munters; Nicky Pieters; Karen Smeets; Bianca Cox; Ann Cuypers; Frans Fierens; Joris Penders; Jaco Vangronsveld; Wilfried Gyselaers; Tim S Nawrot
Journal:  Environ Health Perspect       Date:  2012-05-24       Impact factor: 9.031
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  122 in total

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3.  Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit+ Cardiac Progenitor Cells.

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Journal:  Stem Cells       Date:  2019-01-30       Impact factor: 6.277

4.  Pleiotropic Role of p53 in Injury and Liver Regeneration after Acetaminophen Overdose.

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Journal:  Am J Pathol       Date:  2018-04-11       Impact factor: 4.307

5.  Mitochondrial Impairment in Well-Suppressed Children with Perinatal HIV-Infection on Antiretroviral Therapy.

Authors:  Jing Shen; Afaaf Liberty; Stephanie Shiau; Renate Strehlau; Sheila Pierson; Faeezah Patel; LiQun Wang; Megan Burke; Avy Violari; Ashraf Coovadia; Elaine J Abrams; Stephen Arpadi; Marc Foca; Louise Kuhn
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Journal:  Mol Cell       Date:  2019-01-30       Impact factor: 17.970

7.  Tranexamic acid suppresses the release of mitochondrial DNA, protects the endothelial monolayer and enhances oxidative phosphorylation.

Authors:  Igor Prudovsky; Damien Carter; Doreen Kacer; Monica Palmeri; Tee Soul; Chloe Kumpel; Kathleen Pyburn; Karyn Barrett; Victoria DeMambro; Ilya Alexandrov; Irina Brandina; Robert Kramer; Joseph Rappold
Journal:  J Cell Physiol       Date:  2019-04-02       Impact factor: 6.384

8.  Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans.

Authors:  Anthony L Luz; Joel N Meyer
Journal:  Mitochondrion       Date:  2016-08-23       Impact factor: 4.160

Review 9.  Alternative Applications of Genotyping Array Data Using Multivariant Methods.

Authors:  David C Samuels; Jennifer E Below; Scott Ness; Hui Yu; Shuguang Leng; Yan Guo
Journal:  Trends Genet       Date:  2020-08-06       Impact factor: 11.639

10.  MitoNEET Deficiency Alleviates Experimental Alcoholic Steatohepatitis in Mice by Stimulating Endocrine Adiponectin-Fgf15 Axis.

Authors:  Xudong Hu; Alvin Jogasuria; Jiayou Wang; Chunki Kim; Yoonhee Han; Hong Shen; Jiashin Wu; Min You
Journal:  J Biol Chem       Date:  2016-08-29       Impact factor: 5.157
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