| Literature DB >> 25307892 |
Danishmalik Rafiq Sayyed1, Satish Balasaheb Nimse, Keum-Soo Song, Nackmoon Sung, Taisun Kim.
Abstract
Multiplex SNP discrimination in the multiple codons of the genomic DNA is demonstrated by applying controller DNA technology (CDT) to MDR-TB 9G DNAChips. CDT allowed the efficient detection of 20 SNPs in five codons of the genomic DNA in 40 min. CDT could distinguish SNP targets to as low as 1 copy of the genomic DNA. 100% agreement with the sequencing analysis of clinical samples highlighted the clinical applicability of MDR-TB 9G DNAChips.Entities:
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Year: 2014 PMID： 25307892 DOI： 10.1039/c4cc06625a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222