Literature DB >> 25305305

The etiology, risk factors, and interactions of enteric infections and malnutrition and the consequences for child health and development study (MAL-ED): description of the Tanzanian site.

Estomih R Mduma1, Jean Gratz2, Crystal Patil3, Kristine Matson2, Mary Dakay1, Sarah Liu4, John Pascal1, Lauren McQuillin2, Emmanuel Mighay1, Elizabeth Hinken2, Alexandra Ernst5, Caroline Amour1, Regisiana Mvungi1, Eliwaza Bayyo1, Yeconia Zakaria1, Sokoine Kivuyo6, Eric R Houpt2, Erling Svensen7.   

Abstract

The Haydom, Tanzania, site (TZH) of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) Study is in north-central Tanzania, 300 km from the nearest urban center. TZH is in a remote rural district where most of the population are agropastoralists and grow maize as the staple food. The average household size is 7. The average woman achieves a parity of 6 and has 1 child death. Socioeconomic indicators are poor, with essentially no household having access to electricity, piped water, or improved sanitary facilities (compared with 14%, 7%, and 12%, respectively, reported nationally). The Demographic Health Survey Tanzania 2004 indicated that the region had high rates of stunting and underweight (40% and 31% of children aged <5 years had a height-for-age z score and weight-for-age z score, respectively, of <-2 ) and an under-5 child mortality rate of 5.8%. Human immunodeficiency virus prevalence among 18-month-old children is <0.5%. TZH represents a remote rural African population with profound poverty and malnutrition, but a strong community-based research infrastructure.
© The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  MAL-ED; Tanzania; child development; enteric infections; malnutrition

Mesh:

Year:  2014        PMID: 25305305     DOI: 10.1093/cid/ciu439

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  37 in total

1.  Pharmacokinetics of First-Line Drugs Among Children With Tuberculosis in Rural Tanzania.

Authors:  Museveni Justine; Anita Yeconia; Ingi Nicodemu; Domitila Augustino; Jean Gratz; Estomih Mduma; Scott K Heysell; Sokoine Kivuyo; Sayoki Mfinanga; Charles A Peloquin; Theodore Zagurski; Gibson S Kibiki; Blandina Mmbaga; Eric R Houpt; Tania A Thomas
Journal:  J Pediatric Infect Dis Soc       Date:  2020-02-28       Impact factor: 3.164

2.  Longitudinal Assessment of Antibiotic Resistance in Fecal Escherichia coli in Tanzanian Children.

Authors:  Molly E Fleece; Rosemary Nshama; Thomas Walongo; Caroline Kimathi; Jean Gratz; Elizabeth T Rogawski McQuade; Jie Liu; Suporn Pholwat; Esto Mduma; Eric R Houpt; James A Platts-Mills
Journal:  Am J Trop Med Hyg       Date:  2019-05       Impact factor: 2.345

3.  Evaluating associations between vaccine response and malnutrition, gut function, and enteric infections in the MAL-ED cohort study: methods and challenges.

Authors:  Christel Hoest; Jessica C Seidman; William Pan; Ramya Ambikapathi; Gagandeep Kang; Margaret Kosek; Stacey Knobler; Carl J Mason; Mark Miller
Journal:  Clin Infect Dis       Date:  2014-11-01       Impact factor: 9.079

4.  Rotavirus Infection and Disease in a Multisite Birth Cohort: Results From the MAL-ED Study.

Authors:  Venkata Raghava Mohan; Ramanujam Karthikeyan; Sudhir Babji; Monica McGrath; Sanjaya Shrestha; Jasmin Shrestha; Estomih Mdumah; Caroline Amour; Amidou Samie; Emanuel Nyathi; Rashidul Haque; Shahida Qureshi; Pablo Peñataro Yori; Aldo A M Lima; Ladaporn Bodhidatta; Erling Svensen; Pascal Bessong; Tahmeed Ahmed; Jessica C Seidman; Anita K M Zaidi; Margaret N Kosek; Richard L Guerrant; Jean Gratz; James A Platts-Mills; Dennis R Lang; Michael Gottlieb; Eric R Houpt; Gagandeep Kang
Journal:  J Infect Dis       Date:  2017-08-01       Impact factor: 5.226

5.  Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED).

Authors:  James A Platts-Mills; Sudhir Babji; Ladaporn Bodhidatta; Jean Gratz; Rashidul Haque; Alexandre Havt; Benjamin Jj McCormick; Monica McGrath; Maribel Paredes Olortegui; Amidou Samie; Sadia Shakoor; Dinesh Mondal; Ila Fn Lima; Dinesh Hariraju; Bishnu B Rayamajhi; Shahida Qureshi; Furqan Kabir; Pablo P Yori; Brenda Mufamadi; Caroline Amour; J Daniel Carreon; Stephanie A Richard; Dennis Lang; Pascal Bessong; Esto Mduma; Tahmeed Ahmed; Aldo Aam Lima; Carl J Mason; Anita Km Zaidi; Zulfiqar A Bhutta; Margaret Kosek; Richard L Guerrant; Michael Gottlieb; Mark Miller; Gagandeep Kang; Eric R Houpt
Journal:  Lancet Glob Health       Date:  2015-07-19       Impact factor: 26.763

6.  Disease surveillance methods used in the 8-site MAL-ED cohort study.

Authors:  Stephanie A Richard; Leah J Barrett; Richard L Guerrant; William Checkley; Mark A Miller
Journal:  Clin Infect Dis       Date:  2014-11-01       Impact factor: 9.079

7.  An Exposome Perspective on Environmental Enteric Dysfunction.

Authors:  Job O Mapesa; Amy L Maxwell; Elizabeth P Ryan
Journal:  Environ Health Perspect       Date:  2015-12-29       Impact factor: 9.031

Review 8.  Tropical and travel-associated norovirus: current concepts.

Authors:  Sarah-Blythe Ballard; Mayuko Saito; Andrew J Mirelman; Caryn Bern; Robert H Gilman
Journal:  Curr Opin Infect Dis       Date:  2015-10       Impact factor: 4.915

9.  Urban-Rural Disparities in the Magnitude and Determinants of Stunting among Children under Five in Tanzania: Based on Tanzania Demographic and Health Surveys 1991-2016.

Authors:  Wenjun Zhu; Si Zhu; Bruno F Sunguya; Jiayan Huang
Journal:  Int J Environ Res Public Health       Date:  2021-05-13       Impact factor: 3.390

10.  Population intervention effects in observational studies to emulate target trial results: reconciling the effects of improved sanitation on child growth.

Authors:  Elizabeth T Rogawski McQuade; Jade Benjamin-Chung; Daniel Westreich; Benjamin F Arnold
Journal:  Int J Epidemiol       Date:  2022-02-18       Impact factor: 9.685

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