Literature DB >> 25303011

Suspected flunixin poisoning of a wild Eurasian Griffon Vulture from Spain.

Irene Zorrilla1, Rosa Martinez, Mark A Taggart, Ngaio Richards.   

Abstract

Exposure to residues of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac present in livestock carcasses has caused extensive declines in 3 Gyps vulture species across Asia. The carcass of a wild Eurasian Griffon Vulture (Gyps fulvus) was found in 2012 on an Andalucian (Spain) game hunting reserve and examined forensically. The bird had severe visceral gout, a finding consistent with Gyps vultures from Asia that have been poisoned by diclofenac. Liver and kidney samples from this Eurasian Griffon Vulture contained elevated flunixin (an NSAID) levels (median = 2.70 and 6.50 mg/kg, respectively). This is the first reported case of a wild vulture being exposed to and apparently killed by an NSAID outside Asia. It is also the first reported instance of mortality in the wild resulting from environmental exposure to an NSAID other than diclofenac.
© 2014 Society for Conservation Biology.

Entities:  

Keywords:  Old World vulture; aves carroñeras; avian scavenger; buitres del Viejo Mundo; diclofenac; diclofenaco; ecopharmacovigilance; ketoprofen; ketoprofeno; medicamentos antiinflamatorios no esteroideos; nefrotoxicidad; nephrotoxicity; nonsteroidal anti-inflammatory drug; vigilancia farmacológica

Mesh:

Substances:

Year:  2014        PMID: 25303011     DOI: 10.1111/cobi.12417

Source DB:  PubMed          Journal:  Conserv Biol        ISSN: 0888-8892            Impact factor:   6.560


  4 in total

Review 1.  Practical approaches to adverse outcome pathway development and weight-of-evidence evaluation as illustrated by ecotoxicological case studies.

Authors:  Kellie A Fay; Daniel L Villeneuve; Carlie A LaLone; You Song; Knut Erik Tollefsen; Gerald T Ankley
Journal:  Environ Toxicol Chem       Date:  2017-03-31       Impact factor: 3.742

2.  Tracking pan-continental trends in environmental contamination using sentinel raptors-what types of samples should we use?

Authors:  S Espín; A J García-Fernández; D Herzke; R F Shore; B van Hattum; E Martínez-López; M Coeurdassier; I Eulaers; C Fritsch; P Gómez-Ramírez; V L B Jaspers; O Krone; G Duke; B Helander; R Mateo; P Movalli; C Sonne; N W van den Brink
Journal:  Ecotoxicology       Date:  2016-03-05       Impact factor: 2.823

3.  The Safety and Pharmacokinetics of Carprofen, Flunixin and Phenylbutazone in the Cape Vulture (Gyps coprotheres) following Oral Exposure.

Authors:  Tamsyn Fourie; Duncan Cromarty; Neil Duncan; Kerri Wolter; Vinny Naidoo
Journal:  PLoS One       Date:  2015-10-29       Impact factor: 3.240

4.  Validation of Multi-Residue Method for Quantification of Antibiotics and NSAIDs in Avian Scavengers by Using Small Amounts of Plasma in HPLC-MS-TOF.

Authors:  Pilar Gómez-Ramírez; Guillermo Blanco; Antonio Juan García-Fernández
Journal:  Int J Environ Res Public Health       Date:  2020-06-06       Impact factor: 3.390

  4 in total

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