Literature DB >> 25302238

Clear Cell Carcinoma of Cervix in a 60- year-old Woman: A Case Report.

Kumar Ramesh1, Shruthi S A2, Saraswati P3, Rathnamala M Desai4, Anil K3.   

Abstract

Clear cell carcinoma of cervix is a rare entity amongst cervical neoplasms especially post diethylstilbestrol era. It is hypothesised to have a bimodal distribution with spontaneous cases unrelated to DES exposure observed in elderly age group. We report a rare case of clear cell carcinoma of cervix (CCCC) in a 60-year-old Asian female with no history of diethylstilbestrol (DES) ingestion. She underwent radical hysterectomy and adjuvant radiotherapy and showed no signs of recurrence even after 6 moths of follow up. Review of relevant literature was done including possible aetiology, appropriate treatment and prognostic factors.

Entities:  

Keywords:  Cervical cancer; Clear cell adenocarcinoma; Diethylstilbestrol; Human papilloma virus

Year:  2014        PMID: 25302238      PMCID: PMC4190762          DOI: 10.7860/JCDR/2014/8428.4654

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

Review 1.  Behavior of estrogen-associated female genital tract cancer and its relation to neoplasia following intrauterine exposure to diethylstilbestrol (DES).

Authors:  A L Herbst
Journal:  Gynecol Oncol       Date:  2000-02       Impact factor: 5.482

2.  Clear cell adenocarcinoma of the vagina and cervix. An update of the central Netherlands registry showing twin age incidence peaks.

Authors:  A Hanselaar; M van Loosbroek; O Schuurbiers; T Helmerhorst; J Bulten; J Bernhelm
Journal:  Cancer       Date:  1997-06-01       Impact factor: 6.860

3.  Clear-cell adenocarcinoma of the vagina and cervix in girls: analysis of 170 registry cases.

Authors:  A L Herbst; S J Robboy; R E Scully; D C Poskanzer
Journal:  Am J Obstet Gynecol       Date:  1974-07-01       Impact factor: 8.661

Review 4.  The current status of the DES-exposed population.

Authors:  A L Herbst
Journal:  Obstet Gynecol Annu       Date:  1981

5.  Outcomes of patients undergoing radical hysterectomy for cervical cancer of high-risk histological subtypes.

Authors:  Sonika Agarwal; Kathleen M Schmeler; Pedro T Ramirez; Charlotte C Sun; Alpa Nick; Ricardo Dos Reis; Jubilee Brown; Michael Frumovitz
Journal:  Int J Gynecol Cancer       Date:  2011-01       Impact factor: 3.437

6.  Clear cell adenocarcinoma of the cervix unrelated to diethylstilbestrol exposure.

Authors:  P F Kaminski; R C Maier
Journal:  Obstet Gynecol       Date:  1983-12       Impact factor: 7.661

7.  Primary cervical cancer truly negative for high-risk human papillomavirus is a rare but distinct entity that can affect virgins and young adolescents.

Authors:  C Liebrich; O Brummer; R Von Wasielewski; G Wegener; C Meijer; T Iftner; K U Petry
Journal:  Eur J Gynaecol Oncol       Date:  2009       Impact factor: 0.196

8.  Clear cell carcinoma of the cervix: a multi-institutional review in the post-DES era.

Authors:  M Bijoy Thomas; Jason D Wright; Aliza L Leiser; Dennis S Chi; David G Mutch; Karl C Podratz; Sean C Dowdy
Journal:  Gynecol Oncol       Date:  2008-04-03       Impact factor: 5.482

Review 9.  Adenocarcinoma of the cervix.

Authors:  M A Quinn
Journal:  Ann Acad Med Singapore       Date:  1998-09       Impact factor: 2.473

  9 in total

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