Literature DB >> 25301846

Novel targets in head and neck cancer: should we be optimistic?

Gabriel S Krigsfeld1, Christine H Chung2.   

Abstract

Head and neck squamous cell carcinomas have distinct mutation and copy-number profiles depending on human papillomavirus status. Although several challenges remain in biomarker implementation and clinical trial feasibility, incorporating available genomic data will expedite the development of novel therapeutics and predictive biomarker-driven clinical trials. See related article by Seiwert et al., p. 632. ©2014 American Association for Cancer Research.

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Year:  2014        PMID： 25301846      PMCID： PMC4316824          DOI： 10.1158/1078-0432.CCR-14-1776

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  8 in total

1.  Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma.

Authors:  Carole Fakhry; Qiang Zhang; Phuc Felix Nguyen-Tan; David Rosenthal; Adel El-Naggar; Adam S Garden; Denis Soulieres; Andy Trotti; Vilija Avizonis; John Andrew Ridge; Jonathan Harris; Quynh-Thu Le; Maura Gillison
Journal:  J Clin Oncol       Date:  2014-06-23       Impact factor: 44.544

2.  Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.

Authors:  Nishant Agrawal; Mitchell J Frederick; Curtis R Pickering; Chetan Bettegowda; Kyle Chang; Ryan J Li; Carole Fakhry; Tong-Xin Xie; Jiexin Zhang; Jing Wang; Nianxiang Zhang; Adel K El-Naggar; Samar A Jasser; John N Weinstein; Lisa Treviño; Jennifer A Drummond; Donna M Muzny; Yuanqing Wu; Laura D Wood; Ralph H Hruban; William H Westra; Wayne M Koch; Joseph A Califano; Richard A Gibbs; David Sidransky; Bert Vogelstein; Victor E Velculescu; Nickolas Papadopoulos; David A Wheeler; Kenneth W Kinzler; Jeffrey N Myers
Journal:  Science       Date:  2011-07-28       Impact factor: 47.728

3.  The mutational landscape of head and neck squamous cell carcinoma.

Authors:  Nicolas Stransky; Ann Marie Egloff; Aaron D Tward; Aleksandar D Kostic; Kristian Cibulskis; Andrey Sivachenko; Gregory V Kryukov; Michael S Lawrence; Carrie Sougnez; Aaron McKenna; Erica Shefler; Alex H Ramos; Petar Stojanov; Scott L Carter; Douglas Voet; Maria L Cortés; Daniel Auclair; Michael F Berger; Gordon Saksena; Candace Guiducci; Robert C Onofrio; Melissa Parkin; Marjorie Romkes; Joel L Weissfeld; Raja R Seethala; Lin Wang; Claudia Rangel-Escareño; Juan Carlos Fernandez-Lopez; Alfredo Hidalgo-Miranda; Jorge Melendez-Zajgla; Wendy Winckler; Kristin Ardlie; Stacey B Gabriel; Matthew Meyerson; Eric S Lander; Gad Getz; Todd R Golub; Levi A Garraway; Jennifer R Grandis
Journal:  Science       Date:  2011-07-28       Impact factor: 47.728

4.  Tobacco and alcohol and the risk of head and neck cancer.

Authors:  H Maier; A Dietz; U Gewelke; W D Heller; H Weidauer
Journal:  Clin Investig       Date:  1992 Mar-Apr

5.  Case-control study of human papillomavirus and oropharyngeal cancer.

Authors:  Gypsyamber D'Souza; Aimee R Kreimer; Raphael Viscidi; Michael Pawlita; Carole Fakhry; Wayne M Koch; William H Westra; Maura L Gillison
Journal:  N Engl J Med       Date:  2007-05-10       Impact factor: 91.245

6.  Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas.

Authors:  Tanguy Y Seiwert; Zhixiang Zuo; Michaela K Keck; Arun Khattri; Chandra S Pedamallu; Thomas Stricker; Christopher Brown; Trevor J Pugh; Petar Stojanov; Juok Cho; Michael S Lawrence; Gad Getz; Johannes Brägelmann; Rebecca DeBoer; Ralph R Weichselbaum; Alexander Langerman; Louis Portugal; Elizabeth Blair; Kerstin Stenson; Mark W Lingen; Ezra E W Cohen; Everett E Vokes; Kevin P White; Peter S Hammerman
Journal:  Clin Cancer Res       Date:  2014-07-23       Impact factor: 12.531

Review 7.  Impact of HPV-related head and neck cancer in clinical trials: opportunity to translate scientific insight into personalized care.

Authors:  Christine H Chung; David L Schwartz
Journal:  Otolaryngol Clin North Am       Date:  2012-05-30       Impact factor: 3.346

8.  Mutational landscape and significance across 12 major cancer types.

Authors:  Cyriac Kandoth; Michael D McLellan; Fabio Vandin; Kai Ye; Beifang Niu; Charles Lu; Mingchao Xie; Qunyuan Zhang; Joshua F McMichael; Matthew A Wyczalkowski; Mark D M Leiserson; Christopher A Miller; John S Welch; Matthew J Walter; Michael C Wendl; Timothy J Ley; Richard K Wilson; Benjamin J Raphael; Li Ding
Journal:  Nature       Date:  2013-10-17       Impact factor: 49.962
  8 in total
  1 in total

1.  Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma.

Authors:  Katharina Seidensaal; Andre Nollert; Agnes Hiou Feige; Marie Muller; Thomas Fleming; Nikolas Gunkel; Karim Zaoui; Niels Grabe; Wilko Weichert; Klaus-Josef Weber; Peter Plinkert; Christian Simon; Jochen Hess
Journal:  Mol Cancer       Date:  2015-12-03       Impact factor: 27.401
  1 in total

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